Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405803 | 0.90 | AKT1 (0.52) | AKT1ALDH1A1TDP1MAPK1TSHR | |
| SCHEMBL27463521 | 0.87 | TDP1 (0.50) | AKT1ALDH1A1TDP1MAPK1TSHR | |
| SCHEMBL20492517 | 0.77 | AKT1 (0.52) | AKT1ALDH1A1TDP1MAPK1TSHR | |
| SCHEMBL7315142 | 0.75 | AKT1 (0.50) | AKT1ALDH1A1TDP1MAPK1TSHR | |
| SCHEMBL11583231 | 0.74 | TDP1 (0.56) | AKT1ALDH1A1TDP1MAPK1TSHR | |
| SCHEMBL7327451 | 0.73 | AKT1 (0.48) | AKT1ALDH1A1TDP1MAPK1TSHR | |
| SCHEMBL2134534 | 0.73 | AKT1 (0.48) | AKT1ALDH1A1TSHRCES2CES1 | |
| SCHEMBL7313020 | 0.73 | AKT1 (0.48) | AKT1ALDH1A1TDP1MAPK1TSHR | |
| SCHEMBL15200615 | 0.73 | CES2 (0.47) | ALDH1A1TDP1TSHRCES2CES1 | |
| SCHEMBL17988374 | 0.73 | CES2 (0.48) | ALDH1A1MAPK1CES2CES1NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080241427-A1 | Optical retardation compensation film having positive C-plate and at least one negative C-plate; LCD device; optical switches and waveguides | AKRON POLYMER SYSTEMS | 2008-10-02 | — | — | US | disclosed |