Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14045487 | 0.87 | AKT1 (0.47) | TDP1ALDH1A1MAPK1CES1CES2 | |
| SCHEMBL11583231 | 0.81 | TDP1 (0.56) | TDP1ALDH1A1MAPK1CES1CES2 | |
| SCHEMBL12342000 | 0.79 | ALDH1A1 (0.48) | TDP1ALDH1A1MAPK1CES1CES2 | |
| SCHEMBL6405803 | 0.79 | AKT1 (0.52) | TDP1ALDH1A1MAPK1CES1CES2 | |
| SCHEMBL6317037 | 0.77 | HSD11B1 (0.48) | TDP1ALDH1A1MAPK1CES1CES2 | |
| SCHEMBL1151269 | 0.77 | TDP1 (0.46) | TDP1ALDH1A1MAPK1CES1CES2 | |
| SCHEMBL14855512 | 0.76 | TDP1 (0.47) | TDP1ALDH1A1MAPK1CES1CES2 | |
| SCHEMBL1574223 | 0.74 | CES1 (0.55) | TDP1ALDH1A1MAPK1CES1CES2 | |
| SCHEMBL11267268 | 0.74 | CES1 (0.55) | TDP1ALDH1A1MAPK1CES1CES2 | |
| SCHEMBL9412774 | 0.73 | HSD11B1 (0.44) | TDP1ALDH1A1MAPK1CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101812050-A | Ortho-carbonyl benzamide pesticide | DEQUN SUN | 2010-08-25 | — | — | CN | claimed |
| CN-101812050-A | Ortho-carbonyl benzamide pesticide | DEQUN SUN | 2010-08-25 | — | — | CN | disclosed |
| CN-101812050-A | Ortho-carbonyl benzamide pesticide | DEQUN SUN | 2010-08-25 | — | — | CN | disclosed |
| CN-101812050-A | Ortho-carbonyl benzamide pesticide | DEQUN SUN | 2010-08-25 | — | — | CN | disclosed |
| CN-1146545-C | Benzoylpyridazines | Ĭ��ר���ɷ�����˾ | 2004-04-21 | — | — | CN | disclosed |
| CN-1360581-A | Benzoylpyridazines | MERCK PATENT GMBH (DE) | 2002-07-24 | — | — | CN | disclosed |
| CN-1140451-A | Novel 1, 2-indan-2-mercaptoacetamide disulfide derivatives as enkephalinase inhibitors | MERRELL DOW PHARMA (US) | 1997-01-15 | — | — | CN | disclosed |