Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138723 | 0.89 | HTT (0.34) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL20446047 | 0.83 | MAPK1 (0.31) | MAPK1HIF1AHTT | |
| SCHEMBL719638 | 0.83 | THRB (0.38) | MAPK1HIF1AHTT | |
| SCHEMBL11365400 | 0.82 | ALDH1A1 (0.43) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL13917721 | 0.81 | SERPINE1 (0.31) | HTT | |
| SCHEMBL5597509 | 0.79 | — | — | |
| SCHEMBL2138230 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL9297828 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL11363390 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL26832067 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059173-A1 | DENDRITIC MOLECULES | THE UNIVERSITY OF QUEENSLAND (AU) | 2012-03-08 | — | — | US | disclosed |
| EP-2147042-A1 | DENDRITIC MOLECULES | The University Of Queensland (AU) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008141357-A1 | DENDRITIC MOLECULES | THE UNIVERSITY OF QUEENSLAND (AU) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059173-A1 | DENDRITIC MOLECULES | CD40LG, CD40, TLR3 | ALDH1A1 3696/4885TP53 2178/4885CYP3A4 4516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.