Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20446047 | 0.93 | MAPK1 (0.31) | HTTMAPK1HIF1A | |
| SCHEMBL719638 | 0.89 | THRB (0.38) | HTTMAPK1HIF1A | |
| SCHEMBL140455 | 0.89 | ALDH1A1 (0.41) | HTTMAPK1HIF1AALDH1A1TP53 | |
| SCHEMBL14301460 | 0.86 | — | — | |
| SCHEMBL5597509 | 0.85 | — | — | |
| SCHEMBL11658473 | 0.81 | CHRM2 (0.33) | HTTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13346809 | 0.79 | ALDH1A1 (0.41) | HTTMAPK1HIF1AALDH1A1TP53 | |
| SCHEMBL13917721 | 0.78 | SERPINE1 (0.31) | HTTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13857062 | 0.76 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL21811604 | 0.76 | ZDHHC7 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883941-B2 | Methods and apparatus for controlled single electron transfer living radical polymerization | HENKEL CORPORATION (US) | 2014-11-11 | — | — | US | claimed |
| US-20140275448-A1 | METHODS AND APPARATUS FOR CONTROLLED SINGLE ELECTRON TRANSFER LIVING RADICAL POLYMERIZATION | HENKEL CORPORATION (US) | 2014-09-18 | — | — | US | claimed |
| US-20120053296-A1 | CURABLE COMPOSITIONS WITH MOISTURE-CURABLE FUNCTIONALITY CLUSTERS NEAR THE CHAIN ENDS | HENKEL CORPORATION (US) | 2012-03-01 | — | — | US | claimed |
| JP-2011524942-A | — | — | 2011-09-08 | — | — | JP | claimed |
| EP-2291412-A2 | APPARATUS AND METHODS FOR CONTROLLED RADICAL POLYMERIZATION | Henkel Corporation (US) | 2011-03-09 | — | — | EP | claimed |
| US-11814533-B2 | Curable polymeric coatings for functional surface preparations | CORNELL UNIVERSITY (US) | 2023-11-14 | — | — | US | disclosed |
| US-11008414-B2 | Polymer materials for contact lens applications | CIS PHARMA AG (CH) | 2021-05-18 | — | — | US | disclosed |
| US-20200283560-A1 | New polymer materials for contact lens applications | CIS PHARMA AG (CH) | 2020-09-10 | — | — | US | disclosed |
| US-20200216708-A1 | CURABLE POLYMERIC COATINGS FOR FUNCTIONAL SURFACE PREPARATIONS | CORNELL UNIVERSITY | 2020-07-09 | — | — | US | disclosed |
| EP-2596062-B1 | SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS | ROHM & HAAS (US) | 2019-09-18 | — | — | EP | disclosed |
| EP-3356433-B1 | NEW POLYMER MATERIALS FOR CONTACT LENS APPLICATIONS | CIS PHARMA AG (CH) | 2019-09-18 | — | — | EP | disclosed |
| US-10273314-B2 | Set-LRP polymerization of acrylates in the presence of acids | ROHM AND HAAS COMPANY (US) | 2019-04-30 | — | — | US | disclosed |
| US-20100240858-A1 | PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS | PIOTREK CO., LTD. (JP) | 2010-09-23 | — | — | US | disclosed |
| WO-2010065809-A1 | POLYVINYL CHLORIDE CONTAINING MULTIARMED STAR COPOLYMERS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-06-10 | — | — | WO | disclosed |
| EP-2147042-A1 | DENDRITIC MOLECULES | The University Of Queensland (AU) | 2010-01-27 | — | — | EP | disclosed |
| EP-2013240-A1 | PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS | PIOTREK CO., LTD. (JP) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008141357-A1 | DENDRITIC MOLECULES | THE UNIVERSITY OF QUEENSLAND (AU) | 2008-11-27 | — | — | WO | disclosed |
| WO-2007115939-A1 | PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS | PIOTREK CO., LTD. (JP) | 2007-10-18 | — | — | WO | disclosed |
| US-7157537-B2 | α-Halogenated acid esters with polyvalent alcohols as atom transfer radical polymerization initiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-01-02 | — | — | US | disclosed |
| US-7157537-B2 | α-Halogenated acid esters with polyvalent alcohols as atom transfer radical polymerization initiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283560-A1 | New polymer materials for contact lens applications | CRYAA, CRYAB, BCAT1 | HTT 998/4885MAPK1 567/4885HIF1A 947/4885 |
| US-11008414-B2 | Polymer materials for contact lens applications | CRYAA, BCAT1, CRYAB | HTT 585/4885MAPK1 848/4885HIF1A 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.