Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862271 | 0.78 | ALDH1A1 (0.45) | ALDH1A1NAPRTDAOTSHRSMN1; SMN2 | |
| Phthalic Acid SCHEMBL11784201 | 0.78 | ALDH1A1 (0.93) | ALDH1A1ALOX15AKR1C3POLBNAPRT | |
| SCHEMBL24556547 | 0.77 | MAPT (0.47) | ALDH1A1AKR1C3POLBSMN1; SMN2KMT2A | |
| Phthalic Acid SCHEMBL30665138 | 0.75 | TSHR (0.78) | ALDH1A1ALOX15AKR1C3POLBNAPRT | |
| Phthalic Acid SCHEMBL4578569 | 0.75 | TSHR (0.78) | ALDH1A1ALOX15AKR1C3POLBNAPRT | |
| Phthalic Acid SCHEMBL322997 | 0.75 | TSHR (0.78) | ALDH1A1ALOX15AKR1C3POLBNAPRT | |
| SCHEMBL18793082 | 0.75 | ALDH1A1 (0.61) | ALDH1A1ALOX15AKR1C3POLBNAPRT | |
| Phthalic Acid SCHEMBL30575217 | 0.75 | ALDH1A1 (0.88) | ALDH1A1ALOX15AKR1C3POLBNAPRT | |
| Phthalic Acid SCHEMBL4396104 | 0.75 | ALDH1A1 (0.88) | ALDH1A1ALOX15AKR1C3POLBNAPRT | |
| Phthalic Acid SCHEMBL4797005 | 0.75 | ALDH1A1 (0.88) | ALDH1A1ALOX15AKR1C3POLBNAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367038-B2 | Blocking or activation of endogenous proteins variations rncoded by mutated gees | HMI Medical Innovations, LLC (US) | 2013-02-05 | — | — | US | disclosed |
| US-20080269262-A1 | Blocking or activation of endogenous proteins variations rncoded by mutated gees | HMI MEDICAL INNOVATIONS, LLC. | 2008-10-30 | — | — | US | disclosed |
| WO-2007037898-A2 | THERAMUTEIN MODULATORS | HOUSEY PHARMACEUTICALS INC (US) | 2007-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269262-A1 | Blocking or activation of endogenous proteins variations rncoded by mutated gees | SERBP1, SERPINA6, UBE2V1 | ALDH1A1 3621/4885ALOX15 4695/4885AKR1C3 4126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.