Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.78 |
| ▸ | DAO | P14920 | 1/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.78 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.73 |
| ▸ | CES2 | O00748 | 1/20 | 0.64 |
| ▸ | CES1 | P23141 | 1/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL4578569 | 1.00 | TSHR (0.78) | TSHRALDH1A1NAPRTDAOALOX15 | |
| Phthalic Acid SCHEMBL30665138 | 1.00 | TSHR (0.78) | TSHRALDH1A1NAPRTDAOALOX15 | |
| Phthalic Acid SCHEMBL5078834 | 0.97 | TSHR (0.74) | TSHRALDH1A1NAPRTDAOALOX15 | |
| Phthalic Acid SCHEMBL28331573 | 0.97 | TSHR (0.74) | TSHRALDH1A1NAPRTDAOALOX15 | |
| Phthalic Acid SCHEMBL29055925 | 0.97 | TSHR (0.74) | TSHRALDH1A1NAPRTDAOALOX15 | |
| Terephthalic Acid SCHEMBL108623 | 0.94 | ALDH1A1 (0.78) | TSHRALDH1A1NAPRTDAOALOX15 | |
| Terephthalic Acid SCHEMBL7796434 | 0.92 | ALDH1A1 (0.74) | TSHRALDH1A1NAPRTDAOALOX15 | |
| Phthalic Acid SCHEMBL7750890 | 0.91 | ALDH1A1 (0.64) | TSHRALDH1A1NAPRTDAOALOX15 | |
| Benzoic Acid SCHEMBL7719037 | 0.88 | TSHR (1.00) | TSHRALDH1A1NAPRTDAOALOX15 | |
| Phthalic Acid SCHEMBL1808 | 0.88 | ALDH1A1 (1.00) | TSHRALDH1A1NAPRTDAOALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240203666-A1 | Advanced Polymer Dispersion and a Capacitor on its Base | KEMET ELECTRONICS CORPORATION | 2024-06-20 | — | — | US | claimed |
| WO-2023095183-A1 | A PHARMACEUTICAL COMPOSITION AND A SOLID DOSAGE FORM THEREOF | JORDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (JO) | 2023-06-01 | — | — | WO | claimed |
| US-20230135608-A1 | PHARMACEUTICAL COMPOSITION CONTAINING DIMETHYL FUMARATE AS AN ACTIVE INGREDIENT PROVIDES A SPECIFIC PHARMACOKINETIC PARAMETER | CURACLE CO., LTD. (KR) | 2023-05-04 | — | — | US | claimed |
| US-20230058942-A1 | EXTENDED RELEASE MULTIPARTICULATES OF RANOLAZINE | SUN PHARMACEUTICAL IND LTD (IN) | 2023-02-23 | — | — | US | claimed |
| CN-113645962-A | Enteric coated tablet containing dimethyl fumarate | 库拉科有限公司 | 2021-11-12 | — | — | CN | claimed |
| US-20210228488-A1 | EXTENDED RELEASE COMPOSITIONS AND PROCESS FOR PREPARATION | RUBICON RES PRIVATE LIMITED (IN) | 2021-07-29 | — | — | US | claimed |
| US-20210106537-A1 | EXTENDED RELEASE MULTIPARTICULATES OF RANOLAZINE | SUN PHARMACEUTICAL IND LTD (IN) | 2021-04-15 | — | — | US | claimed |
| US-10898444-B2 | Extended release multiparticulates of ranolazine | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2021-01-26 | — | — | US | claimed |
| WO-2020242132-A1 | ENTERIC TABLET CONTAINING DIMETHYL FUMARATE | 주식회사 큐라클 | 2020-12-03 | — | — | WO | claimed |
| EP-1898886-B1 | NOVEL SUSTAINED RELEASE DOSAGE FORM | RUBICON RES PVT LTD (IN) | 2019-09-04 | — | — | EP | claimed |
| EP-0515626-B1 | STERILISING COMPOSITION | CITROSIL SANITAS SPA (IT) | 1995-12-27 | — | — | EP | claimed |
| WO-1995016739-A1 | STABILISED VINYL CHLORIDE COMPOSITION | AKCROS CHEMICALS (GB) | 1995-06-22 | — | — | WO | claimed |
| EP-0515626-A1 | STERILISING COMPOSITION. | GLAXO SPA (IT) | 1992-12-02 | — | — | EP | claimed |
| WO-1992010935-A1 | STERILISING COMPOSITION | GLAXO S.P.A. (IT) | 1992-07-09 | — | — | WO | claimed |
| EP-0122815-B1 | ENTERIC-SOLUBLE PREPARATIONS AND A PROCESS FOR THEIR PRODUCTION | SANKYO COMPANY LIMITED (JP) | 1989-10-25 | — | — | EP | claimed |
| EP-0108504-B1 | A PROCESS FOR COATING SOLID PHARMACEUTICAL PREPARATIONS AND COATED PREPARATIONS THUS OBTAINED | SANKYO COMPANY LIMITED (JP) | 1987-05-13 | — | — | EP | claimed |
| US-4661162-A | MIXTURE OF POLYMER WITH POLYANIONIC POLYMER WHICH IS SOLUBLE AT LOW PH | SANKYO COMPANY, LIMITED (JP) | 1987-04-28 | — | — | US | claimed |
| US-4497847-A | MONO AND DIESTERS OF GLYCEROL AND SATURATED CARBOXYLIC ACIDS AS PLASTICIZERS | SANKYO COMPANY, LIMITED (JP) | 1985-02-05 | — | — | US | claimed |
| EP-0122815-A1 | Enteric-soluble preparations and a process for their production | SANKYO COMPANY LIMITED (JP) | 1984-10-24 | — | — | EP | claimed |
| EP-0108504-A1 | A process for coating solid pharmaceutical preparations and coated preparations thus obtained | SANKYO COMPANY LIMITED (JP) | 1984-05-16 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230135608-A1 | PHARMACEUTICAL COMPOSITION CONTAINING DIMETHYL FUMARATE AS AN ACTIVE INGREDIENT PROVIDES A SPECIFIC PHARMACOKINETIC PARAMETER | SLC5A2, FH, SLC5A1 | TSHR 4784/4885ALDH1A1 1455/4885NAPRT 2020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.