Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14047539 | 0.85 | SCD (0.53) | SCDKDM4EALDH1A1 | |
| SCHEMBL14047581 | 0.82 | ALDH1A1 (0.45) | SCDALDH1A1 | |
| SCHEMBL14047595 | 0.81 | SCD (0.56) | SCDALDH1A1 | |
| SCHEMBL14047625 | 0.81 | SCD (0.57) | SCDTP53ALDH1A1MAPT | |
| SCHEMBL14047400 | 0.81 | SCD (0.57) | SCDTP53ALDH1A1MAPT | |
| SCHEMBL14047531 | 0.78 | SCD (0.41) | SCDALDH1A1 | |
| SCHEMBL14047603 | 0.77 | SCD (0.57) | SCDLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL244276 | 0.77 | SCD (0.75) | SCD | |
| SCHEMBL14047582 | 0.74 | ALDH1A1 (0.41) | SCDLMNAALDH1A1AADAT | |
| SCHEMBL14047553 | 0.72 | SCD (0.47) | SCDTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127349-A2 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LIPID LEVEL | NOVARTIS AG (CH) | 2008-10-23 | — | — | WO | disclosed |