Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | SCD | O00767 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14047539 | 0.83 | SCD (0.53) | ALDH1A1SCDPOLBKMT2ACYP2C9 | |
| SCHEMBL14047531 | 0.81 | SCD (0.41) | ALDH1A1SCDPOLBKMT2ACYP3A4 | |
| SCHEMBL14047581 | 0.80 | ALDH1A1 (0.45) | ALDH1A1USP2SCDPOLBFKBP1A | |
| SCHEMBL14047595 | 0.79 | SCD (0.56) | ALDH1A1SCDCYP3A4 | |
| SCHEMBL14047625 | 0.79 | SCD (0.57) | ALDH1A1SCDSMN1; SMN2KMT2A | |
| SCHEMBL14047400 | 0.79 | SCD (0.57) | ALDH1A1SCDSMN1; SMN2KMT2A | |
| SCHEMBL243756 | 0.76 | SCD (0.69) | SCD | |
| SCHEMBL14047407 | 0.74 | SCD (0.44) | ALDH1A1SCDLMNAAADAT | |
| SCHEMBL14047553 | 0.72 | SCD (0.47) | ALDH1A1USP2SCDPOLBSMN1; SMN2 | |
| SCHEMBL14047421 | 0.69 | SCD (0.59) | ALDH1A1SCDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127349-A2 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LIPID LEVEL | NOVARTIS AG (CH) | 2008-10-23 | — | — | WO | disclosed |