Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3810327 | 0.91 | KMO (0.34) | ALDH1A1KMOKDM4EHPGDTSHR | |
| SCHEMBL3819720 | 0.87 | KMO (0.32) | ALDH1A1KMOKDM4EHPGDTSHR | |
| SCHEMBL14048263 | 0.83 | TOP1 (0.40) | TTRALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL13717716 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDTSHRRAB9A | |
| SCHEMBL14048262 | 0.77 | TOP1 (0.49) | TTRALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL4397020 | 0.77 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL3812812 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL3814338 | 0.73 | TOP1 (0.35) | ALDH1A1KDM4EHPGDTSHRRAB9A | |
| SCHEMBL13799060 | 0.72 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL3819336 | 0.72 | TOP1 (0.33) | ALDH1A1KDM4EHPGDTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255060-A1 | Ester Linked Macrolides Useful For The Treatment of Microbial Infections | GLAXOSMITHKLINE ISTRAZIVACKI CENTER ZAGREB (HR) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255060-A1 | Ester Linked Macrolides Useful For The Treatment of Microbial Infections | CYP51A1, TLR5, MALT1 | TTR 2227/4885PLAU 3031/4885ALDH1A1 2370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.