Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634848 | 0.79 | SLC6A4 (0.48) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11929876 | 0.76 | LMNA (0.42) | RIPK1AOC3MEN1KMT2AKIF11 | |
| SCHEMBL8612795 | 0.73 | GRIN1 (0.40) | CYP3A4CYP2D6RIPK1LMNASMN1; SMN2 | |
| SCHEMBL27282950 | 0.73 | GRIN1 (0.40) | CYP3A4CYP2D6RIPK1LMNASMN1; SMN2 | |
| SCHEMBL5164111 | 0.73 | RIPK1 (0.48) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| Hydrogen Peroxide SCHEMBL2318659 | 0.72 | TAAR1 (0.50) | KIF11 | |
| SCHEMBL28351624 | 0.71 | KIF11 (0.36) | CYP2D6MEN1KMT2AKIF11LMNA | |
| SCHEMBL845807 | 0.71 | ESR2 (0.47) | SLC6A4SLC6A3KIF11LMNASIGMAR1 | |
| SCHEMBL27968373 | 0.71 | AOC3 (0.48) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8612132 | 0.70 | LMNA (0.39) | CYP3A4CYP2D6RIPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130538-A1 | DEGASSING COMPOSITIONS FOR CURABLE COATINGS | TROY TECHNOLOGY CORPORATION, INC. (US) | 2008-10-30 | — | — | WO | disclosed |