Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5039793 | 0.92 | GAA (0.34) | RXRARXRBRXRGGAACRHR1 | |
| SCHEMBL14031211 | 0.85 | PKM (0.33) | RXRARXRBRXRGCRHR1 | |
| SCHEMBL5046718 | 0.84 | RXRA (0.31) | RXRARXRBRXRG | |
| SCHEMBL14049595 | 0.82 | RXRA (0.32) | RXRARXRBRXRGCRHR1 | |
| SCHEMBL14049519 | 0.82 | RXRA (0.30) | RXRARXRBRXRG | |
| SCHEMBL5043792 | 0.82 | RXRA (0.30) | RXRARXRBRXRG | |
| SCHEMBL5039390 | 0.81 | POLB (0.43) | RXRARXRBRXRGCRHR1 | |
| SCHEMBL5047426 | 0.80 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL5044922 | 0.79 | CRHR1 (0.38) | CRHR1 | |
| SCHEMBL5044714 | 0.78 | RXRA (0.33) | RXRARXRBRXRGGAACRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432283-B2 | Heterocyclic GABAA subtype selective receptor modulators | ROCHE PALO ALTO LLC (US) | 2008-10-07 | — | — | US | disclosed |