Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015055 | 0.83 | POLB (0.48) | POLBLMNARXFP1ALDH1A1MEN1 | |
| SCHEMBL552657 | 0.83 | POLB (0.47) | POLBLMNARXFP1ALDH1A1MEN1 | |
| SCHEMBL4664059 | 0.75 | POLB (0.45) | POLBLMNARXFP1ALDH1A1MEN1 | |
| SCHEMBL10211381 | 0.72 | POLB (0.45) | POLBLMNARXFP1ALDH1A1MEN1 | |
| SCHEMBL13322052 | 0.71 | POLB (0.48) | POLBLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL10211383 | 0.70 | TSHR (0.46) | POLBLMNAALDH1A1GAAPKM | |
| SCHEMBL22859030 | 0.68 | GRIA1 (0.51) | LMNAALDH1A1KMT2A | |
| SCHEMBL4644440 | 0.65 | MAPT (0.49) | RXFP1ALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL31306041 | 0.65 | MAPT (0.49) | RXFP1ALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL29723775 | 0.65 | GPR119 (0.50) | POLBLMNARXFP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269291-A1 | Chemical Compounds | GLAXOSMITHKLINE LLC | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269291-A1 | Chemical Compounds | IDO2, IKBKG, NFKBIA | POLB 1481/4885LMNA 3169/4885RXFP1 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.