Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14049696 | 0.88 | NR1H4 (0.36) | PTPN1NR1H4HSD17B10TDP1RORC | |
| SCHEMBL14049860 | 0.87 | ROCK2 (0.35) | PTPN1NR1H4HSD17B10TDP1RORC | |
| SCHEMBL14049803 | 0.86 | NR1H4 (0.35) | PTPN1NR1H4HSD17B10TDP1RORC | |
| SCHEMBL14049793 | 0.86 | ROCK2 (0.35) | PTPN1NR1H4HSD17B10TDP1RORC | |
| SCHEMBL14049788 | 0.82 | NR1H4 (0.33) | PTPN1NR1H4HSD17B10TDP1RORC | |
| SCHEMBL14049664 | 0.82 | PTPN1 (0.40) | PTPN1NR1H4HSD17B10TDP1RORC | |
| SCHEMBL14049851 | 0.82 | NR1H4 (0.41) | PTPN1NR1H4HSD17B10TDP1RORC | |
| SCHEMBL13628286 | 0.82 | RORC (0.54) | RORC | |
| SCHEMBL14049781 | 0.81 | NR1H4 (0.35) | PTPN1PARP1NR1H4HSD17B10TDP1 | |
| SCHEMBL14049905 | 0.81 | HIF1A (0.39) | HIF1APTPN1NR1H4HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127364-A2 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MYRIAD GENETICS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |