Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 8/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14049696 | 0.94 | NR1H4 (0.36) | NR1H4TRPV1POLBHSD17B10TDP1 | |
| SCHEMBL14049803 | 0.92 | NR1H4 (0.35) | NR1H4TRPV1POLBHSD17B10TDP1 | |
| SCHEMBL14049830 | 0.90 | ROCK2 (0.34) | ROCK2POLBKDM5BROCK1CYP3A4 | |
| SCHEMBL14049793 | 0.90 | ROCK2 (0.35) | ROCK2NR1H4TRPV1HSD17B10TDP1 | |
| SCHEMBL13637776 | 0.88 | TRPV1 (0.42) | NR1H4TRPV1RORC | |
| SCHEMBL14049788 | 0.88 | NR1H4 (0.33) | NR1H4HSD17B10TDP1PTPN1RORC | |
| SCHEMBL14049674 | 0.87 | TRPV1 (0.34) | ROCK2NR1H4TRPV1HSD17B10TDP1 | |
| SCHEMBL14049789 | 0.87 | TRPV1 (0.33) | ROCK2NR1H4TRPV1HSD17B10TDP1 | |
| SCHEMBL14049859 | 0.87 | HIF1A (0.39) | NR1H4HSD17B10TDP1PTPN1RORC | |
| SCHEMBL14049664 | 0.86 | PTPN1 (0.40) | ROCK2NR1H4TRPV1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127364-A2 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MYRIAD GENETICS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |