Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989262 | 0.87 | KMT2A (0.52) | ALDH1A1HPGDMAPK1MEN1KMT2A | |
| SCHEMBL14039758 | 0.84 | ALDH1A1 (0.42) | ALDH1A1HPGDMEN1KMT2ACYP2C19 | |
| SCHEMBL16509294 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HPGDMAPK1MEN1KMT2A | |
| SCHEMBL2986910 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPK1MEN1KMT2A | |
| SCHEMBL14039455 | 0.79 | ALKBH5 (0.39) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL4428122 | 0.79 | MEN1 (0.54) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL4601571 | 0.79 | ALDH1A1 (0.70) | ALDH1A1HPGDMAPK1MEN1KMT2A | |
| SCHEMBL14039537 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPK1MEN1KMT2A | |
| SCHEMBL19220492 | 0.74 | TSHR (0.39) | ALDH1A1MEN1KMT2ALMNAGAA | |
| SCHEMBL5819265 | 0.74 | MEN1 (0.49) | ALDH1A1HPGDMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129080-A1 | 4, 6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES | INGENIUM PHARMACEUTICALS GMBH (DE) | 2008-10-30 | — | — | WO | disclosed |