Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 1.00 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 1.00 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18513474 | 1.00 | HDAC6 (1.00) | HDAC6HDAC8CES2CES1EPHX1 | |
| SCHEMBL3077769 | 1.00 | HDAC6 (1.00) | HDAC6HDAC8CES2CES1EPHX1 | |
| SCHEMBL18513475 | 1.00 | HDAC6 (1.00) | HDAC6HDAC8CES2CES1EPHX1 | |
| SCHEMBL5140992 | 1.00 | HDAC6 (1.00) | HDAC6HDAC8CES2CES1EPHX1 | |
| Hydrochloric Acid SCHEMBL27745682 | 0.97 | HDAC6 (0.95) | HDAC6HDAC8CES2CES1EPHX1 | |
| Potassium SCHEMBL32681950 | 0.97 | HDAC6 (0.95) | HDAC6HDAC8CES2CES1EPHX1 | |
| SCHEMBL17980862 | 0.97 | — | — | |
| SCHEMBL4787787 | 0.92 | — | — | |
| SCHEMBL4100806 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL28105943 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200223807-A1 | Synthesis Of Benzodiazepine Derivatives | TRIO MEDICINES LIMITED (GB) | 2020-07-16 | — | — | US | disclosed |
| EP-1706205-B1 | A CATALYTICAL ASYMMETRIC EPOXIDATION | UNIV CHICAGO (US) | 2008-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200223807-A1 | Synthesis Of Benzodiazepine Derivatives | GABRA1, GABRA5, GABRE | HDAC6 816/4885HDAC8 1874/4885CES2 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.