SCHEMBL1405322

SCHEMBL1405322

CCCCCCSCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 1.00
GMNN O75496 1/20 1.00
TP53 P04637 1/20 1.00
POLB P06746 1/20 1.00
MAPT P10636 1/20 1.00
THRB P10828 1/20 1.00
CYP2C9 P11712 1/20 1.00
BLM P54132 1/20 1.00
CES2 O00748 3/20 0.69
CES1 P23141 5/20 0.60
FAAH O00519 4/20 0.60
PLA2G6 O60733 1/20 0.60
GPR84 Q9NQS5 7/20 0.50
PPARG P37231 7/20 0.50
PPARD Q03181 7/20 0.50
PPARA Q07869 7/20 0.50
HDAC11 Q96DB2 5/20 0.50
TSHR P16473 4/20 0.50
PTPN1 P18031 3/20 0.50
ALDH1A1 P00352 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1405362 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL3638014 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL4814083 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
Tetradecylthioacetic Acid SCHEMBL207756 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL1405316 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL1405566 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL939761 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL4354732 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL4649866 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
Tetradecylthioacetic Acid SCHEMBL7524926 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3962917-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS Momentive Performance Materials Inc. (US) 2022-03-09 EP claimed
US-10919920-B2 Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2021-02-16 US claimed
US-20200347084-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS MOMENTIVE PERFORMANCE MATERIALS INC. 2020-11-05 US claimed
WO-2020223068-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-11-05 WO claimed
JP-3095240-A None JP disclosed
EP-4013819-B1 LATEX FOR BONDING FIBER STRUCTURES SYNTHOMER DEUTSCHLAND GMBH (DE) 2024-01-24 EP disclosed
EP-3555198-B1 CURABLE POLYMER LATEX COMPOSITIONS FOR THE MANUFACTURE OF RUBBER ARTICLES SYNTHOMER SDN BHD (MY) 2023-09-20 EP disclosed
EP-3530804-B1 LATEX BONDED TEXTILE FIBER STRUCTURE FOR CONSTRUCTION APPLICATIONS SYNTHOMER DEUTSCHLAND GMBH (DE) 2023-09-06 EP disclosed
US-20220282016-A1 LATEX FOR BONDING FIBER STRUCTURES SYNTHOMER DEUTSCHLAND GMBH (DE) 2022-09-08 US disclosed
EP-4013819-A1 LATEX FOR BONDING FIBER STRUCTURES Synthomer Deutschland GmbH (DE) 2022-06-22 EP disclosed
EP-3962917-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS Momentive Performance Materials Inc. (US) 2022-03-09 EP disclosed
US-11230621-B2 Curable polymer latex compositions for the manufacture of rubber articles Synthomer Sdn. Bhd 2022-01-25 US disclosed
US-5362473-A Dry aerosol MALLINCKRODT MEDICAL, INC. (US) 1994-11-08 US disclosed
US-5362878-A Intermediates for making N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase (ACAT) PFIZER INC. (US) 1994-11-08 US disclosed
EP-0438527-A4 RADIOLABELLED PARTICULATE COMPOSITION 1992-07-01 EP disclosed
EP-0438527-A1 RADIOLABELLED PARTICULATE COMPOSITION MALLINCKRODT, INC. (US) 1991-07-31 EP disclosed
JP-H0395240-A RUBBER COMPOSITION HAVING IMPROVED PROCESSABILITY MONSANTO EUROPE SA 1991-04-19 JP disclosed
WO-1990003803-A1 RADIOLABELLED PARTICULATE COMPOSITION MALLINCKRODT, INC. (US) 1990-04-19 WO disclosed
EP-0080969-B1 A METHOD OF REMOVING RESIDUAL ACRYLONITRILE FROM LATEX SYSTEMS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-02-05 EP disclosed
US-4399253-A REACTION WITH THIOL THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919920-B2 Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters TST, MPST, APEH HSD17B10 323/4885GMNN 1105/4885TP53 4369/4885
US-20200347084-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS TST, MPST, APEH HSD17B10 323/4885GMNN 1105/4885TP53 4369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.