SCHEMBL1405339

SCHEMBL1405339

O=C(O)CCC(=O)OCC(COC(=O)CCC(=O)O)(COC(=O)CCC(=O)O)COC(=O)CCC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.45
EGLN1 Q9GZT9 4/20 0.45
ALKBH5 Q6P6C2 1/20 0.45
SUCNR1 Q9BXA5 1/20 0.45
KDM5C P41229 3/20 0.43
PHF8 Q9UPP1 3/20 0.43
KDM2A Q9Y2K7 3/20 0.43
KDM6B O15054 2/20 0.43
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 2/20 0.39
HIF1A Q16665 1/20 0.39
SLC15A2 Q16348 1/20 0.36
SLC13A3 Q8WWT9 1/20 0.36
OR51E2 Q9H255 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.35
TSHR P16473 2/20 0.34
ADRA2A P08913 1/20 0.34
ADRA1A P35348 1/20 0.34
PAM P19021 2/20 0.33
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11912289 1.00 LMNA (0.45) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL12809711 0.93 LMNA (0.40) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL2139466 0.89 MAPK1 (0.41) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL26239179 0.88 LMNA (0.37) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL10727715 0.86 LMNA (0.50) LMNAALDH1A1SLC22A6TSHRPAM
SCHEMBL233528 0.84 ALDH1A1 (0.56) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL751094 0.83 TSHR (0.39) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL30477176 0.82 THRB (0.41) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL542102 0.82 EGLN1 (0.38) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL12009552 0.82 TSHR (0.37) LMNAEGLN1ALKBH5SUCNR1KDM5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1966294-B1 POLYAMIDE MOLDING MATERIALS LANXESS DEUTSCHLAND GMBH (DE) 2011-03-09 EP claimed
EP-0655070-B1 TRIANTENNARY CLUSTER GLYCOSIDES, THEIR PREPARATION AND USE UNIV LEIDEN (NL) 1998-07-22 EP claimed
US-20230295514-A1 Mesogen Compounds TRANSITIONS OPTICAL, LTD. (IE) 2023-09-21 US disclosed
US-9080127-B2 Composition, compound and film forming method FUJIFILM CORPORATION (JP) 2015-07-14 US disclosed
US-20120201962-A1 COMPOSITION, COMPOUND AND FILM FORMING METHOD FUJIFILM CORPORATION (JP) 2012-08-09 US disclosed
EP-1966294-B1 POLYAMIDE MOLDING MATERIALS LANXESS DEUTSCHLAND GMBH (DE) 2011-03-09 EP disclosed
EP-1966294-B1 POLYAMIDE MOLDING MATERIALS LANXESS DEUTSCHLAND GMBH (DE) 2011-03-09 EP disclosed
US-7754819-B2 Thermoplastic elastomer YOKOHAMA RUBBER CO., LTD. (JP) 2010-07-13 US disclosed
US-7754819-B2 Thermoplastic elastomer YOKOHAMA RUBBER CO., LTD. (JP) 2010-07-13 US disclosed
US-20090030099-A1 FOAM COMPOSITION AND FOAM THE YOKOHAMA RUBBER CO., LTD. (JP) 2009-01-29 US disclosed
US-20090030099-A1 FOAM COMPOSITION AND FOAM THE YOKOHAMA RUBBER CO., LTD. (JP) 2009-01-29 US disclosed
EP-1966294-A1 POLYAMIDE MOLDING MATERIALS Lanxess Deutschland GmbH (DE) 2008-09-10 EP disclosed
WO-2007079873-A1 POLYAMIDE MOLDING MATERIALS LANXESS DEUTSCHLAND GMBH (DE) 2007-07-19 WO disclosed
WO-2007079873-A1 POLYAMIDE MOLDING MATERIALS LANXESS DEUTSCHLAND GMBH (DE) 2007-07-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120201962-A1 COMPOSITION, COMPOUND AND FILM FORMING METHOD PYM1, DEGS1, ALK LMNA 736/4885EGLN1 1177/4885ALKBH5 208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.