Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL16594863 | 1.00 | TSHR (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL28066982 | 0.93 | MEN1 (0.52) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL3137828 | 0.92 | — | — | |
| SCHEMBL14872240 | 0.92 | — | — | |
| SCHEMBL3141634 | 0.92 | — | — | |
| Ethylene Glycol SCHEMBL2723632 | 0.87 | ALDH1A1 (0.35) | TSHRMAPK1ALDH1A1 | |
| Ethylene Glycol SCHEMBL450520 | 0.87 | ALDH1A1 (0.35) | TSHRMAPK1ALDH1A1 | |
| SCHEMBL27780644 | 0.82 | TSHR (0.36) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL4892570 | 0.82 | TSHR (0.53) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL12813939 | 0.82 | TSHR (0.53) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2537875-A1 | NOVEL POLYAZOMETHINE | Soken Chemical & Engineering Co., Ltd. (JP) | 2012-12-26 | — | — | EP | disclosed |
| US-20120302720-A1 | Novel Polyazomethine | SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) | 2012-11-29 | — | — | US | disclosed |