Ethylene Glycol

Ethylene Glycol

SCHEMBL450520

CC(N)COCC(C)N.OCCO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
SCN4A P35499 3/20 0.32
SCN5A Q14524 3/20 0.32
TSHR P16473 3/20 0.32
LMNA P02545 2/20 0.32
SCN1A P35498 2/20 0.32
SCN9A Q15858 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
NFKB1 P19838 1/20 0.32
KCNK3 O14649 1/20 0.32
CACNA1F O60840 1/20 0.32
KCNK2 O95069 1/20 0.32
GBA1 P04062 1/20 0.32
MAOA P21397 1/20 0.32
HTR2A P28223 1/20 0.32
SLC6A4 P31645 1/20 0.32
HTR2B P41595 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL2723632 1.00 ALDH1A1 (0.35) ALDH1A1SCN4ASCN5ATSHRLMNA
SCHEMBL114351 0.87
SCHEMBL30985226 0.87
Di(Hydroxyethyl)Ether SCHEMBL16594863 0.87 TSHR (0.50) ALDH1A1TSHRMAPK1
Di(Hydroxyethyl)Ether SCHEMBL14054643 0.87 TSHR (0.50) ALDH1A1TSHRMAPK1
SCHEMBL3137828 0.83
Propylene Glycol SCHEMBL251122 0.83 TDP1 (0.53) ALDH1A1SCN4ASCN5ATSHRLMNA
Propylene Glycol SCHEMBL27811556 0.83 TDP1 (0.53) ALDH1A1SCN4ASCN5ATSHRLMNA
SCHEMBL14872240 0.83
Propylene Glycol SCHEMBL6567284 0.83 TDP1 (0.53) ALDH1A1SCN4ASCN5ATSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120061083-A1 WELLBORE FLUID AND METHODS OF TREATING AN EARTHEN FORMATION M-I DRILLING FLUIDS UK LIMITED (GB) 2012-03-15 US disclosed