Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13677847 | 1.00 | F10 (0.62) | F10PTGS2 | |
| SCHEMBL14078394 | 0.88 | F10 (0.48) | F10PTGS2 | |
| SCHEMBL1405919 | 0.88 | F10 (0.61) | F10PTGS2 | |
| SCHEMBL1405896 | 0.88 | F10 (0.61) | F10PTGS2 | |
| SCHEMBL13890609 | 0.80 | F10 (0.73) | F10PTGS2 | |
| SCHEMBL13677849 | 0.77 | F10 (0.81) | F10PTGS2 | |
| SCHEMBL6103366 | 0.77 | F10 (0.64) | F10 | |
| SCHEMBL6103360 | 0.77 | F10 (0.64) | F10 | |
| SCHEMBL3134461 | 0.77 | F10 (0.47) | F10PTGS2 | |
| SCHEMBL13678080 | 0.76 | F10 (0.78) | F10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585730-B1 | CARBOXAMIDE DERIVATIVES AND THEIR USE AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2011-03-09 | — | — | EP | disclosed |
| US-7598241-B2 | 2-[3-(4-chlorophenyl)ureido] N-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-4-methanesulfonylbutyramide; prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors | MERCK PATENT GMBH (DE) | 2009-10-06 | — | — | US | disclosed |
| US-20060074072-A1 | Carboxamide derivatives and their use as factor xa inhibitors | MERCK PATENT GMBH (DE) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074072-A1 | Carboxamide derivatives and their use as factor xa inhibitors | F11, F12, F10 | F10 3/4885PTGS2 2047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.