Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ADH1B | P00325 | 1/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.44 |
| ▸ | ADH1A | P07327 | 1/20 | 0.44 |
| ▸ | ADH4 | P08319 | 1/20 | 0.44 |
| ▸ | ADH7 | P40394 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14059969 | 1.00 | TP53 (0.46) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL1001262 | 0.93 | TP53 (0.40) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL14060777 | 0.92 | TP53 (0.44) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL354776 | 0.92 | TP53 (0.44) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL10232491 | 0.92 | TP53 (0.44) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL23001180 | 0.92 | EPHX2 (0.48) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL354775 | 0.92 | TP53 (0.44) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL23001132 | 0.92 | EPHX2 (0.48) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL354867 | 0.92 | TP53 (0.44) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL352993 | 0.92 | TP53 (0.44) | TP53ADH1BADH1CADH1AADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3610868-B1 | AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID DERIVATIVES AND THEIR MEDICAL USE | GRI BIO INC (US) | 2025-02-19 | — | — | EP | disclosed |
| EP-3229811-B1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GRI BIO INC (US) | 2021-02-24 | — | — | EP | disclosed |
| US-10829506-B2 | Amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use | GRI BIO, INC. (US) | 2020-11-10 | — | — | US | disclosed |
| EP-3610868-A1 | AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID, PHOSPHONIC ACID AND CARBOXYLIC ACID DERIVATIVES AND THEIR MEDICAL USE | GRI Bio, Inc. (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-2809318-B1 | AMMONIUM-CONTAINING SULFONIC ACID, PHOSPHONIC ACID AND CARBOXYLIC ACID DERIVATIVES AND THEIR MEDICAL USE | GRI BIO INC (US) | 2019-05-08 | — | — | EP | disclosed |
| US-20180244703-A1 | AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID, PHOSPHONIC ACID AND CARBOXYLIC ACID DERIVATIVES AND THEIR MEDICAL USE | ALTIUM GROWTH FUND, LP | 2018-08-30 | — | — | US | disclosed |
| US-9850265-B2 | Amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use | GRI BIO, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-20160016981-A1 | AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID, PHOSPHONIC ACID AND CARBOXYLIC ACID DERIVATIVES AND THEIR MEDICAL USE | GLYCOREGIMMUNE, INC. (US) | 2016-01-21 | — | — | US | disclosed |
| EP-2809318-A1 | AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID, PHOSPHONIC ACID AND CARBOXYLIC ACID DERIVATIVES AND THEIR MEDICAL USE | Jado Technologies GmbH (DE) | 2014-12-10 | — | — | EP | disclosed |
| WO-2012160187-A1 | AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID, PHOSPHONIC ACID AND CARBOXYLIC ACID DERIVATIVES AND THEIR MEDICAL USE | JADO TECHNOLOGIES GMBH (DE) | 2012-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180244703-A1 | AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID, PHOSPHONIC ACID AND CARBOXYLIC ACID DERIVATIVES AND THEIR MEDICAL USE | AADAT, AASDHPPT, ASS1 | TP53 2319/4885ADH1B 3363/4885ADH1C 3367/4885 |
| US-10829506-B2 | Amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use | AADAT, AASDHPPT, ASS1 | TP53 2319/4885ADH1B 3363/4885ADH1C 3367/4885 |
| US-20160016981-A1 | AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID, PHOSPHONIC ACID AND CARBOXYLIC ACID DERIVATIVES AND THEIR MEDICAL USE | AADAT, AASDHPPT, ASS1 | TP53 2253/4885ADH1B 3418/4885ADH1C 3322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.