Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 9/20 | 0.53 |
| ▸ | PPARA | Q07869 | 8/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727660 | 0.83 | PPARA (0.57) | PPARGPPARAPPARDMAP4K4MEN1 | |
| SCHEMBL5726752 | 0.83 | PPARA (0.60) | PPARGPPARAPPARDMAP4K4MEN1 | |
| SCHEMBL413254 | 0.83 | LMNA (0.81) | LMNAPPARGPPARAALOX15PLA2G4B | |
| SCHEMBL5726351 | 0.82 | PPARA (0.58) | PPARGPPARAPPARDMAP4K4MEN1 | |
| SCHEMBL10254673 | 0.81 | LMNA (0.63) | LMNAPPARGPPARAALOX15PLA2G4B | |
| SCHEMBL7988206 | 0.80 | PPARA (0.55) | LMNAPPARGPPARAPPARDPTPN7 | |
| SCHEMBL15063356 | 0.78 | LMNA (0.74) | LMNAPPARGPPARAALOX15PLA2G4B | |
| SCHEMBL3845579 | 0.78 | PPARG (0.56) | PPARGPPARAPPARDPTPN7MAP4K4 | |
| SCHEMBL30785439 | 0.78 | LMNA (1.00) | LMNAPPARGPPARAALOX15PLA2G4B | |
| SCHEMBL594554 | 0.78 | LMNA (1.00) | LMNAPPARGPPARAALOX15PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012160112-A1 | NOVEL IODINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND USE THEREOF AS AMINATION AGENTS | FUNDACIÓ PRIVADA INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2012-11-29 | — | — | WO | disclosed |