Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.57 |
| ▸ | PPARD | Q03181 | 5/20 | 0.57 |
| ▸ | PPARG | P37231 | 15/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726752 | 0.94 | PPARA (0.60) | PPARAPPARDPPARGMEN1CYP1A2 | |
| SCHEMBL5726351 | 0.93 | PPARA (0.58) | PPARAPPARDPPARGMEN1CYP1A2 | |
| SCHEMBL5727212 | 0.86 | PPARA (0.62) | PPARAPPARDPPARGMEN1CYP1A2 | |
| SCHEMBL14060871 | 0.83 | LMNA (0.64) | PPARAPPARDPPARGMEN1CYP1A2 | |
| SCHEMBL5892213 | 0.83 | PPARA (0.57) | PPARAPPARDPPARGCYP1A2CYP3A4 | |
| SCHEMBL5660178 | 0.81 | PPARA (0.53) | PPARAPPARDPPARGCYP4F2CYP4A11 | |
| SCHEMBL5727498 | 0.80 | PPARG (0.62) | PPARAPPARDPPARGMEN1CYP1A2 | |
| SCHEMBL5892268 | 0.79 | PPARA (0.47) | PPARAPPARDPPARGCYP1A2CYP2D6 | |
| SCHEMBL7988206 | 0.79 | PPARA (0.55) | PPARAPPARDPPARGMEN1CYP1A2 | |
| SCHEMBL5659323 | 0.79 | PPARA (0.54) | PPARAPPARDPPARGCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1502590-B1 | Heterocyclic oxime derivatives, process for their preparation and use thereof in the treatment of type II diabetes | SERVIER LAB (FR) | 2006-12-20 | — | — | EP | disclosed |
| EP-1502590-A1 | Heterocyclic oxime derivatives, process for their preparation and use thereof in the treatment of type II diabetes | Les Laboratoires Servier (FR) | 2005-02-02 | — | — | EP | disclosed |