Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867705 | 0.81 | GAA (0.36) | MGLLCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL27828836 | 0.77 | TYMP (0.32) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL25963065 | 0.74 | KDM5A (0.35) | MGLLBRD4BRD2CHRNB2CHRNB4 | |
| SCHEMBL297012 | 0.73 | HTR2C (0.45) | MGLLBRD4BRD2CHRNB2CHRNB4 | |
| SCHEMBL6799429 | 0.73 | HTR2C (0.33) | MEN1KMT2A | |
| SCHEMBL17185334 | 0.73 | — | — | |
| SCHEMBL31467662 | 0.72 | CHRNB2 (0.40) | MGLLCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL2896725 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL1456315 | 0.72 | HTR2C (0.44) | MGLLBRD4BRD2CHRNB2CHRNB4 | |
| SCHEMBL11842283 | 0.71 | NOS3 (0.45) | MGLLBRD4BRD2KMT2AKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012159262-A1 | SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2012-11-29 | — | — | WO | disclosed |