⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799429 | 0.75 | HTR2C (0.33) | — | |
| SCHEMBL14060967 | 0.72 | MGLL (0.39) | — | |
| SCHEMBL3867705 | 0.71 | GAA (0.36) | — | |
| SCHEMBL29875408 | 0.70 | GAA (0.49) | — | |
| SCHEMBL11100875 | 0.67 | PIK3CD (0.36) | — | |
| Cyclo(Prolylglycyl) SCHEMBL4247464 | 0.67 | ALDH1A1 (0.48) | — | |
| SCHEMBL21736594 | 0.67 | ALDH1A1 (0.48) | — | |
| SCHEMBL21736595 | 0.67 | ALDH1A1 (0.48) | — | |
| SCHEMBL337898 | 0.67 | NOS1 (0.44) | — | |
| SCHEMBL2890715 | 0.67 | NOS1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807678-B2 | Peptidomimetics of biologically active metallopeptides | PALATIN TECHNOLOGIES, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| US-7326707-B2 | Bicyclic melanocortin-specific compounds | PALATIN TECHNOLOGIES INCORPORATED (US) | 2008-02-05 | — | — | US | disclosed |
| EP-1425029-A4 | PEPTIDOMIMETICS OF BIOLOGICALLY ACTIVE METALLOPEPTIDES | PALATIN TECHNOLOGIES INC (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005079574-A1 | BICYCLIC MELANOCORIN-SPECIFIC COMPOUNDS | PALATIN TECHNOLOGIES, INC. (US) | 2005-09-01 | — | — | WO | disclosed |
| US-20040171520-A1 | Peptidomimetics of biologically active metallopeptides | PALATIN TECHNOLOGIES, INC. | 2004-09-02 | — | — | US | disclosed |
| US-20040152134-A1 | Bicyclic melanocortin-specific compounds | PALATIN TECHNOLOGIES, INC. (US) | 2004-08-05 | — | — | US | disclosed |
| EP-1425029-A1 | PEPTIDOMIMETICS OF BIOLOGICALLY ACTIVE METALLOPEPTIDES | Palatin Technologies, Inc. (US) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003013571-A1 | PEPTIDOMIMETICS OF BIOLOGICALLY ACTIVE METALLOPEPTIDES | PALATIN TECHNOLOGIES, INC. (US) | 2003-02-20 | — | — | WO | disclosed |