SCHEMBL1406137

SCHEMBL1406137

C=Cc1ccccc1CC(=O)CCCCC(=O)Cc1ccccc1C=C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
MAPT P10636 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
LMNA P02545 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
AKR1B1 P15121 1/20 0.33
HDAC3 O15379 3/20 0.33
HDAC4 P56524 3/20 0.33
HDAC1 Q13547 3/20 0.33
HDAC7 Q8WUI4 3/20 0.33
HDAC2 Q92769 3/20 0.33
HDAC10 Q969S8 3/20 0.33
HDAC11 Q96DB2 3/20 0.33
HDAC8 Q9BY41 3/20 0.33
HDAC6 Q9UBN7 3/20 0.33
HDAC9 Q9UKV0 3/20 0.33
HDAC5 Q9UQL6 3/20 0.33
CYP2C19 P33261 2/20 0.33
VNN1 O95497 2/20 0.32
THRA P10827 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4443824 0.89 ALDH1A1 (0.40) ALDH1A1MAPTLMNATDP1AKR1B1
SCHEMBL27700960 0.82 IAPP (0.37) ALDH1A1AKR1B1THRATHRBPTGER4
SCHEMBL9403751 0.81 ALDH1A1 (0.38) ALDH1A1MAPTLMNATDP1AKR1B1
SCHEMBL156765 0.79 AKR1B1 (0.55) MAPTTDP1AKR1B1CYP2C19KDM4E
SCHEMBL9346915 0.78 IAPP (0.34) ALDH1A1AKR1B1HDAC3HDAC4HDAC1
SCHEMBL2136288 0.78 ALDH1A1 (0.38) ALDH1A1LMNAAKR1B1SMN1; SMN2
Hydrochloric Acid SCHEMBL10627468 0.78 AKR1B1 (0.53) MAPTTDP1AKR1B1CYP2C19KDM4E
SCHEMBL10864725 0.78 L3MBTL1 (0.45) ALDH1A1MAPTL3MBTL1LMNAAKR1B1
Lithium SCHEMBL29604103 0.78 AKR1B1 (0.53) MAPTTDP1AKR1B1CYP2C19KDM4E
SCHEMBL27976060 0.78 AKR1B1 (0.53) MAPTTDP1AKR1B1CYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8313790-B2 Extracting carbonyl compounds from a drink by extraction with a functionalized inert support CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2012-11-20 US disclosed
EP-1999245-B1 PROCESS FOR EXTRACTING CARBONYLATED COMPOUNDS FROM A DRINK BY LIQUID-SOLID EXTRACTION WITH A FUNCTIONALIZED INERT SUPPORT CENTRE NAT RECH SCIENT (FR) 2011-03-09 EP disclosed
US-20100166930-A1 PROCESS FOR EXTRACTING CARBONYLATED COMPOUNDS FROM A DRINK BY LIQUID-SOLID EXTRACTION WITH A FUNCTIONALIZED INERT SUPPORT CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS ) 2010-07-01 US disclosed
EP-1999245-A1 PROCESS FOR EXTRACTING CARBONYLATED COMPOUNDS FROM A DRINK BY LIQUID-SOLID EXTRACTION WITH A FUNCTIONALIZED INERT SUPPORT CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2008-12-10 EP disclosed
WO-2007107603-A1 PROCESS FOR EXTRACTING CARBONYLATED COMPOUNDS FROM A DRINK BY LIQUID-SOLID EXTRACTION WITH A FUNCTIONALIZED INERT SUPPORT CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2007-09-27 WO disclosed