Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346915 | 0.92 | IAPP (0.34) | IAPPHSD11B1ALDH1A1THRATHRB | |
| SCHEMBL4443824 | 0.89 | ALDH1A1 (0.40) | ALDH1A1THRBAKR1B1CES2CES1 | |
| SCHEMBL1406137 | 0.82 | ALDH1A1 (0.35) | IAPPALDH1A1THRATHRBAKR1B1 | |
| SCHEMBL10864725 | 0.81 | L3MBTL1 (0.45) | IAPPALDH1A1THRATHRBAKR1B1 | |
| SCHEMBL9403751 | 0.81 | ALDH1A1 (0.38) | ALDH1A1THRBAKR1B1PTGER4PTGER3 | |
| SCHEMBL21100152 | 0.80 | IAPP (0.46) | IAPPHSD11B1ALDH1A1AKR1B1CES2 | |
| Bicarbonate SCHEMBL7120281 | 0.79 | GABRA1 (0.40) | ALDH1A1THRATHRBAKR1B1CES2 | |
| SCHEMBL156765 | 0.79 | AKR1B1 (0.55) | AKR1B1 | |
| SCHEMBL29749448 | 0.78 | ALDH1A1 (0.44) | ALDH1A1THRBGABRA1GABRB2 | |
| SCHEMBL14959 | 0.78 | ALDH1A1 (0.44) | ALDH1A1THRBGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101151293-B | Two-component curable aqueous urethane-alkyd resin composition and use thereof | MITSUI CHEMICALS POLYURETHANES | 2010-12-08 | — | — | CN | disclosed |
| CN-101151293-A | Two-component curable aqueous urethane-alkyd resin composition and use thereof | MITSUI CHEMICALS POLYURETHANES (JP) | 2008-03-26 | — | — | CN | disclosed |