Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.46 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.46 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.46 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.46 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.46 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.46 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.46 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.46 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.46 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.46 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.46 |
| ▸ | PSMA8 | Q8TAA3 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL3813642 | 0.97 | CTSS (0.48) | CTSSPOLBPSMB11PSMA7PSMB1 | |
| Leucine SCHEMBL1406209 | 0.85 | CTSS (0.54) | CTSSPOLBCACNA1BCTSL | |
| Leucine SCHEMBL1406330 | 0.85 | CTSS (0.62) | CTSSPOLBPSMB11PSMA7PSMB1 | |
| Leucine SCHEMBL3816835 | 0.83 | CTSS (0.51) | CTSSPOLBCACNA1BCTSL | |
| SCHEMBL234602 | 0.83 | CTSS (0.49) | CTSSPOLBPSMB11PSMA7PSMB1 | |
| Leucine SCHEMBL3812485 | 0.82 | CTSS (0.59) | CTSSPOLBPSMB11PSMA7PSMB1 | |
| SCHEMBL3185566 | 0.82 | CTSS (0.48) | CTSSPOLBPSMB11PSMA7PSMB1 | |
| SCHEMBL6803415 | 0.81 | BLM (0.56) | CTSSPOLBGAACTSLGFER | |
| SCHEMBL7560095 | 0.81 | ITGB3 (0.55) | — | |
| Leucine SCHEMBL1406207 | 0.80 | CTSS (0.47) | CTSSPOLBPSMB11PSMA7PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355910-B1 | FORMULATION OF BORONIC ACID COMPOUNDS | US OF AMERICA REPRESENTED BY THE SECRETARY DEPT OF HEALTH AND HUMAN SERVICES (US) | 2011-03-09 | — | — | EP | claimed |
| EP-0788360-B3 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | MILLENNIUM PHARM INC (US) | 2009-08-12 | — | — | EP | claimed |
| EP-0788360-B1 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | MILLENNIUM PHARM INC (US) | 2003-05-28 | — | — | EP | claimed |