Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 1.00 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 1.00 |
| ▸ | MAOB | P27338 | 9/20 | 0.80 |
| ▸ | MAOA | P21397 | 3/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.72 |
| ▸ | GLA | P06280 | 4/20 | 0.72 |
| ▸ | GAA | P10253 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.72 |
| ▸ | CA12 | O43570 | 2/20 | 0.72 |
| ▸ | CA2 | P00918 | 2/20 | 0.72 |
| ▸ | CA3 | P07451 | 2/20 | 0.72 |
| ▸ | CA4 | P22748 | 2/20 | 0.72 |
| ▸ | CA6 | P23280 | 2/20 | 0.72 |
| ▸ | CA7 | P43166 | 2/20 | 0.72 |
| ▸ | CA9 | Q16790 | 2/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29399552 | 1.00 | MIF (1.00) | MIFPFKFB3MAOBMAOAKDM4E | |
| SCHEMBL30267263 | 0.95 | MIF (0.90) | MIFPFKFB3MAOBMAOAKDM4E | |
| SCHEMBL6417829 | 0.89 | MAOB (1.00) | MIFPFKFB3MAOBMAOAKDM4E | |
| SCHEMBL10855650 | 0.88 | MIF (0.77) | MIFPFKFB3MAOBMAOAKDM4E | |
| SCHEMBL12611191 | 0.87 | MIF (0.78) | MIFPFKFB3MAOBMAOAKDM4E | |
| SCHEMBL10789548 | 0.86 | MIF (0.73) | MIFPFKFB3MAOBMAOAKDM4E | |
| SCHEMBL11595332 | 0.85 | MIF (0.74) | MIFPFKFB3MAOBMAOAKDM4E | |
| SCHEMBL21585388 | 0.85 | MIF (0.74) | MIFPFKFB3MAOBMAOAKDM4E | |
| SCHEMBL11492411 | 0.85 | MIF (0.74) | MIFPFKFB3MAOBMAOAKDM4E | |
| SCHEMBL592309 | 0.85 | MIF (0.73) | MIFPFKFB3MAOBMAOAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630638-B2 | Methods and compositions for diabetes treatment and β-cell regeneration | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-05-19 | — | — | US | claimed |
| US-20250017950-A1 | COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS | UCL BUSINESS LTD (GB) | 2025-01-16 | — | — | US | claimed |
| EP-4433077-A1 | COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS | UCL Business Ltd (GB) | 2024-09-25 | — | — | EP | claimed |
| US-20230165965-A1 | NEW COUMARIN-POLYMER CONJUGATES AND USES THEREOF | ONYEL BIOTECH S.R.L. (IT) | 2023-06-01 | — | — | US | claimed |
| WO-2023089313-A1 | COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS | UCL BUSINESS LTD (GB) | 2023-05-25 | — | — | WO | claimed |
| CN-107446015-B | Coumarin derivative and preparation method and application thereof | 首都医科大学 | 2020-10-16 | — | — | CN | claimed |
| EP-2516666-B1 | METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE | 3M INNOVATIVE PROPERTIES CO (US) | 2016-04-20 | — | — | EP | claimed |
| EP-2718458-B1 | NOVEL METHOD FOR DETECTION OF BETA-D-GLUCURONIDASE | BIOSYNTH AG (CH) | 2015-07-08 | — | — | EP | claimed |
| US-20140212905-A1 | Novel Method for Detection of Beta-D-Glucuronidase | BIOSYNTH AG (CH) | 2014-07-31 | — | — | US | claimed |
| EP-2718458-A1 | NOVEL METHOD FOR DETECTION OF BETA-D-GLUCURONIDASE | Biosynth AG (CH) | 2014-04-16 | — | — | EP | claimed |
| US-8518664-B2 | Methods of determining the amount of microorganisms present in a test sample | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-08-27 | — | — | US | claimed |
| WO-2012168415-A1 | NOVEL METHOD FOR DETECTION OF BETA-D-GLUCURONIDASE | BIOSYNTH AG (CH) | 2012-12-13 | — | — | WO | claimed |
| EP-2532753-A1 | Method for detection of beta-D-glucuronidase | Biosynth AG (CH) | 2012-12-12 | — | — | EP | claimed |
| US-20120302631-A1 | Inhibitors of PFKFB3 for Cancer Therapy | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2012-11-29 | — | — | US | claimed |
| EP-2516666-A1 | METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE | 3M Innovative Properties Company (US) | 2012-10-31 | — | — | EP | claimed |
| US-20120252049-A1 | METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE | 3M INNOVATIVE PROPERTIES COMPANY | 2012-10-04 | — | — | US | claimed |
| WO-2011087711-A1 | METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-07-21 | — | — | WO | claimed |
| US-12630638-B2 | Methods and compositions for diabetes treatment and β-cell regeneration | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-05-19 | — | — | US | disclosed |
| US-4279992-A | Specific binding assay employing an enzyme-cleavable substrate as label | MILES LABORATORIES, INC. (US) | 1981-07-21 | — | — | US | disclosed |
| US-4151291-A | ANALGESICS | UNICLER (FR) | 1979-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165965-A1 | NEW COUMARIN-POLYMER CONJUGATES AND USES THEREOF | CBR3, CYP3A43, CYP3A4 | MIF 2404/4885PFKFB3 850/4885MAOB 3648/4885 |
| US-20120302631-A1 | Inhibitors of PFKFB3 for Cancer Therapy | PFKFB3, PFKFB2, PFKFB1 | MIF 4491/4885PFKFB3 1/4885MAOB 2055/4885 |
| US-12630638-B2 | Methods and compositions for diabetes treatment and β-cell regeneration | IAPP, APP, SLC2A3 | MIF 3464/4885PFKFB3 27/4885MAOB 2636/4885 |
| US-20250017950-A1 | COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS | POLRMT, TK2, GOT2 | MIF 4875/4885PFKFB3 485/4885MAOB 3590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.