Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP8 | P22894 | 3/20 | 0.41 |
| ▸ | REN | P00797 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 8/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL233988 | 0.85 | MMP2 (0.48) | MMP2MMP9MMP8CTSSPSMB5 | |
| SCHEMBL1406323 | 0.84 | CTSS (0.40) | MMP2MMP9MMP8RENCTSS | |
| SCHEMBL1406197 | 0.79 | CTSS (0.40) | CTSSPSMB5PSMB8CTSBCTSL | |
| Leucine SCHEMBL3812226 | 0.77 | MMP2 (0.48) | MMP2MMP9MMP8CTSSPSMB5 | |
| Leucine SCHEMBL2297615 | 0.77 | MMP2 (0.49) | MMP2MMP9MMP8RENCTSS | |
| SCHEMBL9631257 | 0.76 | POLB (0.53) | MMP2MMP9MMP8CTSSTACR1 | |
| SCHEMBL1406024 | 0.76 | CTSS (0.44) | RENCTSSPSMB5PSMB8CTSB | |
| Leucine SCHEMBL1406254 | 0.76 | MMP2 (0.50) | MMP2MMP9MMP8CTSSCTSB | |
| SCHEMBL3469950 | 0.76 | MMP2 (0.43) | MMP2MMP9MMP8RENPSMB5 | |
| SCHEMBL1406185 | 0.75 | GAA (0.38) | MMP2MMP9MMP8TACR1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355910-B1 | FORMULATION OF BORONIC ACID COMPOUNDS | US OF AMERICA REPRESENTED BY THE SECRETARY DEPT OF HEALTH AND HUMAN SERVICES (US) | 2011-03-09 | — | — | EP | claimed |