Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232948 | 0.86 | ITGB3 (0.45) | GAAMAPTNPSR1ITGB3ITGAV | |
| SCHEMBL1406179 | 0.85 | GAA (0.36) | GAAMAPTNPSR1ITGB3ITGAV | |
| Alanine SCHEMBL601223 | 0.84 | ITGB3 (0.44) | GAAMAPTNPSR1ITGB3ITGAV | |
| Leucine SCHEMBL3814957 | 0.78 | ITGB3 (0.45) | GAAMAPTNPSR1ITGB3ITGAV | |
| SCHEMBL31238101 | 0.78 | PSMB5 (0.54) | GAAMAPTNPSR1ITGB3ITGAV | |
| Leucine SCHEMBL1414045 | 0.77 | ITGB3 (0.47) | GAAMAPTNPSR1ITGB3ITGAV | |
| SCHEMBL7217344 | 0.77 | MAPT (0.53) | GAAMAPTNPSR1ITGB3ITGAV | |
| SCHEMBL1406331 | 0.75 | MMP2 (0.41) | TSHRMMP2MMP9MMP8PSMB5 | |
| SCHEMBL3194343 | 0.75 | ITGB3 (0.43) | GAAMAPTNPSR1ITGB3ITGAV | |
| Alanine SCHEMBL3470608 | 0.74 | NTSR1 (0.39) | MEN1KMT2ATSHRNTSR1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355910-B1 | FORMULATION OF BORONIC ACID COMPOUNDS | US OF AMERICA REPRESENTED BY THE SECRETARY DEPT OF HEALTH AND HUMAN SERVICES (US) | 2011-03-09 | — | — | EP | claimed |