SCHEMBL14063413

SCHEMBL14063413

CCc1ccc(N(c2ccc(COC(C)=O)cc2)c2ccc(-c3ccc(N(c4ccc(CC)cc4)c4ccc(COC(C)=O)cc4)cc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.51
HPGD P15428 3/20 0.43
KDM4E B2RXH2 2/20 0.43
NPC1 O15118 2/20 0.43
GAA P10253 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MAPT P10636 4/20 0.42
CYP3A4 P08684 1/20 0.42
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
RAB9A P51151 2/20 0.39
NAAA Q02083 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
EGFR P00533 1/20 0.38
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14063417 1.00 ALDH1A1 (0.51) ALDH1A1HPGDKDM4ENPC1GAA
SCHEMBL14063414 0.95 ALDH1A1 (0.56) ALDH1A1HPGDKDM4ENPC1GAA
SCHEMBL14063390 0.90 ALDH1A1 (0.62) ALDH1A1HPGDKDM4ENPC1GAA
SCHEMBL14063393 0.89 ALDH1A1 (0.64) ALDH1A1HPGDNPC1GAATSHR
SCHEMBL14063397 0.89 ALDH1A1 (0.50) ALDH1A1HPGDKDM4ENPC1GAA
SCHEMBL9581057 0.89 ALDH1A1 (0.64) ALDH1A1HPGDNPC1GAATSHR
SCHEMBL14063398 0.89 ALDH1A1 (0.64) ALDH1A1HPGDNPC1GAATSHR
SCHEMBL14063395 0.86 ALDH1A1 (0.47) ALDH1A1NPC1SMN1; SMN2RAB9A
SCHEMBL10017478 0.86 ALDH1A1 (0.67) ALDH1A1HSD17B10MAPTCYP3A4RXRA
SCHEMBL4198688 0.84 ALDH1A1 (0.69) ALDH1A1NPC1MAPK1MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-20080220356-A1 Electrophotographic photoreceptor, process cartridge and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-09-11 US disclosed
US-20080220356-A1 Electrophotographic photoreceptor, process cartridge and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-09-11 US disclosed