Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132773 | 0.91 | ALDH1A1 (0.78) | ALDH1A1CYP3A4KMT2AMEN1TDP1 | |
| SCHEMBL14063413 | 0.86 | ALDH1A1 (0.51) | ALDH1A1CYP3A4RXRARXRBKMT2A | |
| SCHEMBL14063417 | 0.86 | ALDH1A1 (0.51) | ALDH1A1CYP3A4RXRARXRBKMT2A | |
| SCHEMBL4198688 | 0.84 | ALDH1A1 (0.69) | ALDH1A1CYP3A4KMT2AMEN1NAAA | |
| SCHEMBL11315920 | 0.84 | ALDH1A1 (0.69) | ALDH1A1CYP3A4KMT2AMEN1TDP1 | |
| SCHEMBL10604973 | 0.84 | ALDH1A1 (0.69) | ALDH1A1CYP3A4KMT2AMEN1TDP1 | |
| SCHEMBL1790469 | 0.84 | ALDH1A1 (0.50) | ALDH1A1RXRARXRBKMT2AMEN1 | |
| SCHEMBL126492 | 0.84 | ALDH1A1 (0.69) | ALDH1A1CYP3A4KMT2AMEN1LMNA | |
| SCHEMBL3442816 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP3A4RXRARXRBKMT2A | |
| SCHEMBL14063390 | 0.83 | ALDH1A1 (0.62) | ALDH1A1CYP3A4KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018093-B2 | Hemiasterlin derivatives and antibody-drug conjugates including same | Sumitomo Pharma Co., Ltd. (JP) | 2024-06-25 | — | — | US | disclosed |
| US-11815815-B2 | Composition for forming silicon-containing resist underlayer film removable by wet process | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2023-11-14 | — | — | US | disclosed |
| US-20230346752-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION | 2023-11-02 | — | — | US | disclosed |
| US-20230293497-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION (US) | 2023-09-21 | — | — | US | disclosed |
| US-11717514-B2 | PSMA binding ligand-linker conjugates and methods for using | PURDUE RESEARCH FOUNDATION (US) | 2023-08-08 | — | — | US | disclosed |
| US-11666623-B2 | Tetramaleimide linkers and use thereof | NEWBIO THERAPEUTICS, INC. (CN) | 2023-06-06 | — | — | US | disclosed |
| US-20230132093-A1 | EXTRACELLULAR VESICLE-NLRP3 ANTAGONIST | CODIAK BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | US | disclosed |
| EP-3176156-B1 | ALKYLAMIDOTHIAZOLES, COSMETIC AND DERMATOLOGICAL PREPARATIONS CONTAINING THEM, AND THEIR USE FOR THE TREATMENT AND PROPHYLAXIS OF UNWANTED PIGMENTATION OF THE SKIN | BEIERSDORF AG (DE) | 2019-06-12 | — | — | EP | disclosed |
| EP-2968100-B1 | COMBINATION OF ALKYLAMIDOTHIAZOLES AND PRESERVATIVES | BEIERSDORF AG (DE) | 2019-04-10 | — | — | EP | disclosed |
| US-10010618-B2 | Methods for treating cancer using combination therapies | ENDOCYTE, INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-20110172254-A1 | FOLATE RECEPTOR BINDING CONJUGATES OF ANTIFOLATES | ENDOCYTE, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| US-20110157531-A1 | LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME | SONY CORPORATION (JP) | 2011-06-30 | — | — | US | disclosed |
| US-20110134382-A1 | LIQUID CRYSTAL DISPLAY ELEMENT AND LIQUID CRYSTAL DISPLAY DEVICE | SONY CORPORATION (JP) | 2011-06-09 | — | — | US | disclosed |
| US-20100324008-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION (US) | 2010-12-23 | — | — | US | disclosed |
| US-20100323973-A1 | CONJUGATES CONTAINING HYDROPHILIC SPACER LINKERS | ENDOCTYE, INC. | 2010-12-23 | — | — | US | disclosed |
| US-20100256082-A1 | Metallo-hydrolase inhibitors using metal binding moietes in combination with targeting moieties | VIAMET PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | US | disclosed |
| US-20090203889-A1 | Bivalent linkers and conjugates thereof | ENDOCYTE, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| EP-1335908-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONISTS | LILLY CO ELI (US) | 2008-02-13 | — | — | EP | disclosed |
| US-4873278-A | Inhibition of irradiation yellowing in polysulfone compositions | GENERAL ELECTRIC COMPANY (US) | 1989-10-10 | — | — | US | disclosed |
| EP-0314042-A2 | Novel copolymers and superoxide dismutase modified with said copolymers | KURARAY CO., LTD. (JP) | 1989-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230132093-A1 | EXTRACELLULAR VESICLE-NLRP3 ANTAGONIST | NLRP3, MTREX, NOD1 | ALDH1A1 3391/4885CYP3A4 4783/4885RXRA 3743/4885 |
| US-20230293497-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | FOLH1, KLK3, PSMA1 | ALDH1A1 2843/4885CYP3A4 4369/4885RXRA 2111/4885 |
| US-20090203889-A1 | Bivalent linkers and conjugates thereof | CCNB2, PAICS, FOLR2 | ALDH1A1 1872/4885CYP3A4 587/4885RXRA 197/4885 |
| US-10010618-B2 | Methods for treating cancer using combination therapies | SLC7A11, CXCR2, TPX2 | ALDH1A1 831/4885CYP3A4 3409/4885RXRA 3374/4885 |
| US-20100256082-A1 | Metallo-hydrolase inhibitors using metal binding moietes in combination with targeting moieties | MMEL1, MPI, METAP1 | ALDH1A1 322/4885CYP3A4 616/4885RXRA 3991/4885 |
| US-20100324008-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | FOLH1, KLK3, PSMA1 | ALDH1A1 2843/4885CYP3A4 4369/4885RXRA 2111/4885 |
| US-11717514-B2 | PSMA binding ligand-linker conjugates and methods for using | FOLH1, KLK3, PSMA1 | ALDH1A1 2843/4885CYP3A4 4369/4885RXRA 2111/4885 |
| US-20100323973-A1 | CONJUGATES CONTAINING HYDROPHILIC SPACER LINKERS | CD44, HAVCR2, HCAR1 | ALDH1A1 2723/4885CYP3A4 4431/4885RXRA 1217/4885 |
| US-20230346752-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | FOLH1, KLK3, PSMA1 | ALDH1A1 2843/4885CYP3A4 4369/4885RXRA 2111/4885 |
| US-11666623-B2 | Tetramaleimide linkers and use thereof | MCTS1, CA14, TTL | ALDH1A1 987/4885CYP3A4 4565/4885RXRA 4833/4885 |
| US-12018093-B2 | Hemiasterlin derivatives and antibody-drug conjugates including same | FCGRT, QARS1, INHA | ALDH1A1 1215/4885CYP3A4 261/4885RXRA 1347/4885 |
| US-20110172254-A1 | FOLATE RECEPTOR BINDING CONJUGATES OF ANTIFOLATES | FOLR1, FOLR2, DHFR | ALDH1A1 1044/4885CYP3A4 3643/4885RXRA 558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.