Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15100480 | 0.92 | ABCB1 (0.53) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL14192859 | 0.92 | ABCB1 (0.44) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL14064053 | 0.90 | MEN1 (0.48) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL18637298 | 0.88 | ABCB1 (0.56) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL22851948 | 0.84 | MAOB (0.45) | ABCB1USP2CFTRPAX8ATM | |
| Rhodamine Ii SCHEMBL30320900 | 0.83 | MEN1 (0.64) | ABCB1USP2CFTRPAX8ATM | |
| Rhodamine Ii SCHEMBL12310066 | 0.83 | MEN1 (0.64) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL13660291 | 0.83 | MEN1 (0.46) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL14077551 | 0.83 | MEN1 (0.40) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL15100483 | 0.81 | TGM2 (0.42) | ABCB1USP2CFTRPAX8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623649-B2 | Method of selecting a cardiomyoctye using intracellular mitochondria as an indicator | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-01-07 | — | — | US | disclosed |
| US-20080090266-A1 | Method of Selecting a Cardiomyoctye Using Intracellular Mitochondria as an Indicator | ASUBIO PHARMA CO.,LTD (JP) | 2008-04-17 | — | — | US | disclosed |