Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31685679 | 0.80 | ADORA3 (0.62) | POLBENPP1P2RY1ADORA3TAS1R3 | |
| SCHEMBL31685649 | 0.78 | POLB (0.59) | POLBENPP1P2RY1ADORA3TAS1R3 | |
| SCHEMBL14616841 | 0.77 | HIF1A (0.53) | POLBHIF1AENPP1P2RY1SLC29A1 | |
| SCHEMBL20266320 | 0.77 | POLB (0.58) | POLBHIF1AENPP1P2RY1ADORA1 | |
| SCHEMBL29664985 | 0.76 | POLB (0.61) | POLBENPP1P2RY1ADORA3 | |
| SCHEMBL15721195 | 0.76 | POLB (0.61) | POLBENPP1P2RY1ADORA3 | |
| SCHEMBL3637334 | 0.76 | POLB (0.61) | POLBENPP1P2RY1ADORA3 | |
| SCHEMBL1064092 | 0.76 | POLB (0.61) | POLBENPP1P2RY1ADORA3 | |
| SCHEMBL24059865 | 0.76 | POLB (0.73) | POLBENPP1P2RY1ADORA1TAS1R3 | |
| SCHEMBL6915410 | 0.76 | POLB (0.73) | POLBENPP1P2RY1ADORA1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427675-B2 | Compounds and methods for the characterization of oligonucleotides | ISIS PHARMACEUTICALS, INC. (US) | 2008-09-23 | — | — | US | disclosed |