SCHEMBL29664985

SCHEMBL29664985

CNc1ncnc2c1ncn2[C@H]1C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.77

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.61
P2RY1 P47900 5/20 0.58
P2RY2 P41231 2/20 0.58
P2RX3 P56373 4/20 0.58
P2RX2 Q9UBL9 4/20 0.58
GPR17 Q13304 1/20 0.58
ENPP1 P22413 2/20 0.58
ADORA3 P0DMS8 1/20 0.57
P2RX4 Q99571 1/20 0.57
P2RY6 Q15077 1/20 0.55
P2RY12 Q9H244 1/20 0.55
DTYMK P23919 2/20 0.54
P2RX1 P51575 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1064092 1.00 POLB (0.61) POLBP2RY1P2RY2P2RX3P2RX2
SCHEMBL15721195 1.00 POLB (0.61) POLBP2RY1P2RY2P2RX3P2RX2
SCHEMBL3637334 1.00 POLB (0.61) POLBP2RY1P2RY2P2RX3P2RX2
SCHEMBL26779529 0.92 P2RX3 (0.64) POLBP2RY1P2RY2P2RX3P2RX2
SCHEMBL30381713 0.92 POLB (0.62) POLBP2RY1P2RY2P2RX3P2RX2
SCHEMBL31685679 0.92 ADORA3 (0.62) POLBP2RY1ENPP1ADORA3
SCHEMBL16203365 0.88 POLB (0.64) POLBP2RY1P2RY2P2RX3P2RX2
SCHEMBL29465233 0.87 POLB (0.65) POLBP2RY1P2RY2P2RX3P2RX2
SCHEMBL245486 0.87 POLB (0.65) POLBP2RY1P2RY2P2RX3P2RX2
SCHEMBL1763078 0.87 POLB (0.65) POLBP2RY1P2RY2P2RX3P2RX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120064427-A Method and analysis system for detecting brain nucleic acid hydrolysate spatial distribution based on mass spectrum imaging 北京脑科学与类脑研究所 2025-05-30 CN claimed
EP-4642926-A1 SPATIALLY BARCODED SURFACES Cellanome, Inc. (US) 2025-11-05 EP disclosed
US-20250320542-A1 SPATIALLY BARCODED SURFACES CELLANOME INC (US) 2025-10-16 US disclosed
CN-120064427-A Method and analysis system for detecting brain nucleic acid hydrolysate spatial distribution based on mass spectrum imaging 北京脑科学与类脑研究所 2025-05-30 CN disclosed
US-20250050301-A1 SPATIAL BARCODES BY HYDROGEL LITHOGRAPHY Cellanome, Inc. 2025-02-13 US disclosed
EP-4504972-A1 SPATIAL BARCODES BY HYDROGEL LITHOGRAPHY Cellanome, Inc. (US) 2025-02-12 EP disclosed
WO-2024145393-A1 SPATIALLY BARCODED SURFACES Cellanome, Inc. (US) 2024-07-04 WO disclosed
CN-117795096-A Methods, compositions and kits for preparing sequencing libraries 吉复生物科技有限公司 2024-03-29 CN disclosed
EP-4259819-A1 METHODS FOR DUPLEX REPAIR The Broad Institute Inc. (US) 2023-10-18 EP disclosed
WO-2023196603-A1 SPATIAL BARCODES BY HYDROGEL LITHOGRAPHY Cellanome, Inc. (US) 2023-10-12 WO disclosed
WO-2022125977-A1 METHODS FOR DUPLEX REPAIR THE BROAD INSTITUTE, INC. (US) 2022-06-16 WO disclosed