SCHEMBL142008

SCHEMBL142008

COc1c(C)cc(C(C)(c2ccccc2)c2cc(C)c(OC(=O)c3cccc(C(C)=O)c3)c(C)c2)cc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 8/20 0.38
▸ KMT2A Q03164 5/20 0.38
▸ PKM P14618 2/20 0.38
▸ ESR1 P03372 2/20 0.38
▸ ESR2 Q92731 2/20 0.38
▸ POLB P06746 3/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ GFER P55789 1/20 0.38
▸ TDP1 Q9NUW8 2/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ KIF11 P52732 1/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ LMNA P02545 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ MEN1 O00255 3/20 0.36
▸ THRB P10828 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12346020 0.88 ESR1 (0.41) MAPTKMT2APKMESR1ESR2
SCHEMBL13865060 0.85 ESR1 (0.39) MAPTKMT2APKMESR1ESR2
SCHEMBL13864965 0.85 TSHR (0.44) MAPTKMT2APKMESR1ESR2
SCHEMBL140650 0.84 TSHR (0.45) MAPTKMT2APKMESR1ESR2
SCHEMBL12762428 0.83 MAPT (0.43) MAPTKMT2APKMESR1ESR2
SCHEMBL14007584 0.83 ESR1 (0.39) MAPTKMT2APKMESR1ESR2
SCHEMBL12346032 0.81 MAPT (0.41) MAPTKMT2AESR1ESR2POLB
SCHEMBL16573866 0.81 MAPT (0.42) MAPTKMT2AESR1ESR2POLB
SCHEMBL15001278 0.81 MAPT (0.55) MAPTKMT2APKMESR1ESR2
SCHEMBL12762425 0.80 ALDH1A1 (0.40) MAPTKMT2APKMESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9442400-B2 Electrophotographic photoreceptor including a copolymer polyarylate resin, production method therefor, electrophotographic device including the photoreceptor, and production method for the copolymer polyarylate resin FUJI ELECTRIC CO., LTD. (JP) 2016-09-13 — — US disclosed
US-20150079510-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCTION METHOD THEREFOR, ELECTROPHOTOGRAPHIC DEVICE, AND PRODUCTION METHOD FOR COPOLYMER POLYARYLATE RESIN FUJI ELECTRIC CO., LTD. (JP) 2015-03-19 — — US disclosed
US-8404414-B2 Electrophotographic photoconductor and manufacturing method thereof FUJI ELECTRIC CO., LTD. (JP) 2013-03-26 — — US disclosed
US-20120058422-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, PROCESS FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD (JP) 2012-03-08 — — US disclosed
US-20110189603-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF FUJI ELECTRIC SYSTEMS CO., LTD. (JP) 2011-08-04 — — US disclosed
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