Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | MAOA | P21397 | 5/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14065394 | 1.00 | MAOB (0.49) | MAOBMAOACYP19A1EGFRSLC18A3 | |
| SCHEMBL14065392 | 0.82 | HPGD (0.42) | MAOBMAOA | |
| SCHEMBL14074025 | 0.81 | MAOB (0.39) | MAOBMAOACYP19A1EGFRSLC18A3 | |
| Hydrochloric Acid SCHEMBL16610762 | 0.79 | MAOA (0.46) | MAOBMAOACYP19A1 | |
| Hydrochloric Acid SCHEMBL16610587 | 0.79 | MAOA (0.46) | MAOBMAOACYP19A1 | |
| SCHEMBL14065399 | 0.74 | MAOB (0.41) | MAOBMAOA | |
| SCHEMBL29356757 | 0.69 | TRPC3 (0.48) | MAOBMAOA | |
| SCHEMBL14065393 | 0.68 | CYP19A1 (0.43) | MAOBMAOACYP19A1SLC18A3 | |
| SCHEMBL13162081 | 0.67 | CHRNB2 (0.69) | — | |
| SCHEMBL21399970 | 0.67 | CHRNB2 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423059-B2 | Pharmaceutically active compounds and methods of use | WYETH (US) | 2008-09-09 | — | — | US | disclosed |
| US-7423059-B2 | Pharmaceutically active compounds and methods of use | WYETH (US) | 2008-09-09 | — | — | US | disclosed |