Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 1/20 | 0.48 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL28245885 | 0.90 | TRPC3 (0.56) | TRPC3TRPC6MAOAMAOBRIPK1 | |
| SCHEMBL5197715 | 0.84 | CCNC (0.53) | RIPK1ALDH1A1HSD11B1 | |
| SCHEMBL938757 | 0.84 | RIPK1 (0.59) | TRPC3TRPC6RIPK1PRMT5WDR77 | |
| SCHEMBL5195419 | 0.84 | HSD17B10 (0.58) | MAOAMAOBROCK2PARP14PARP10 | |
| SCHEMBL17142323 | 0.81 | RIPK1 (0.55) | TRPC3TRPC6RIPK1PRMT5WDR77 | |
| SCHEMBL6153199 | 0.81 | OPRD1 (0.46) | RIPK1ROCK2ALDH1A1GAAPOLB | |
| SCHEMBL21425146 | 0.79 | RIPK1 (0.50) | TRPC3TRPC6RIPK1ROCK2HSD11B1 | |
| SCHEMBL38658434 | 0.79 | RIPK1 (0.47) | RIPK1ROCK2ALDH1A1POLBHSD11B1 | |
| SCHEMBL4776278 | 0.79 | RIPK1 (0.65) | RIPK1HSD11B1PARP14PARP10 | |
| Hydrochloric Acid SCHEMBL16610762 | 0.78 | MAOA (0.46) | TRPC3TRPC6MAOAMAOBRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941922-A1 | INHIBITORS OF RAF KINASES | Kinnate Biopharma Inc. (US) | 2022-01-26 | — | — | EP | disclosed |