SCHEMBL14065931

SCHEMBL14065931

O=C(O)c1ccc(N2C(=O)C(=CC=Cc3sc(=S)n(-c4ccc(C(=O)O)cc4)c3O)SC2=S)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.66
POLB P06746 2/20 0.66
ALDH1A1 P00352 2/20 0.66
LMNA P02545 1/20 0.66
HTT P42858 1/20 0.66
PTPN1 P18031 1/20 0.66
DUSP22 Q9NRW4 3/20 0.53
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
MCL1 Q07820 4/20 0.50
BLM P54132 2/20 0.50
ALPG P10696 2/20 0.50
RECQL P46063 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
KDM4E B2RXH2 1/20 0.50
USP2 O75604 1/20 0.50
ALPL P05186 1/20 0.50
ALPI P09923 1/20 0.50
APEX1 P27695 1/20 0.50
GFER P55789 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6738029 0.79 MAPT (1.00) MAPTPOLBALDH1A1LMNAHTT
SCHEMBL10035971 0.76 MEN1 (0.55) MAPTPOLBALDH1A1LMNADUSP22
SCHEMBL6739345 0.75 MAPT (0.78) MAPTPOLBALDH1A1LMNAHTT
SCHEMBL13170370 0.72 DUSP22 (0.70) MAPTPOLBALDH1A1LMNAHTT
SCHEMBL14213564 0.70 MAPT (0.78) MAPTPOLBALDH1A1LMNAHTT
SCHEMBL6789390 0.69 DUSP22 (1.00) MAPTPOLBALDH1A1LMNAHTT
SCHEMBL14213563 0.68 MAPT (0.79) MAPTPOLBALDH1A1LMNAHTT
SCHEMBL24217863 0.67 DUSP22 (1.00) MAPTPOLBALDH1A1LMNAHTT
SCHEMBL12637129 0.67 DUSP22 (0.80) MAPTPOLBALDH1A1LMNAHTT
SCHEMBL6886616 0.66 KMT2A (0.80) MAPTPOLBALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7422843-B2 Color photographic films comprising support having color developable light sensitive silver halide emulsion layers and color dye-forming couplers, used for high speed print reproduction; storage stability, cinematography, uniformity for quality FUJIFILM CORPORATION (JP) 2008-09-09 US disclosed
US-7422843-B2 Color photographic films comprising support having color developable light sensitive silver halide emulsion layers and color dye-forming couplers, used for high speed print reproduction; storage stability, cinematography, uniformity for quality FUJIFILM CORPORATION (JP) 2008-09-09 US disclosed
US-20070248906-A1 Silver halide color photographic light-sensitive material FUJIFILM CORPORATION (JP) 2007-10-25 US disclosed
US-20070248906-A1 Silver halide color photographic light-sensitive material FUJIFILM CORPORATION (JP) 2007-10-25 US disclosed