Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.79 |
| ▸ | MEN1 | O00255 | 10/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.79 |
| ▸ | POLB | P06746 | 5/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.79 |
| ▸ | RECQL | P46063 | 4/20 | 0.79 |
| ▸ | HTT | P42858 | 3/20 | 0.79 |
| ▸ | NPC1 | O15118 | 3/20 | 0.79 |
| ▸ | LMNA | P02545 | 3/20 | 0.79 |
| ▸ | ALPG | P10696 | 2/20 | 0.79 |
| ▸ | THRB | P10828 | 2/20 | 0.79 |
| ▸ | RAB9A | P51151 | 2/20 | 0.79 |
| ▸ | PKM | P14618 | 2/20 | 0.79 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.79 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.79 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14213564 | 0.91 | MAPT (0.78) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL6738029 | 0.89 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL18313731 | 0.88 | ALDH1A1 (0.64) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL14146544 | 0.88 | ALDH1A1 (0.64) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL14213565 | 0.88 | MAPT (0.70) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL4918105 | 0.83 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL4918099 | 0.83 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL30014988 | 0.83 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL12123516 | 0.82 | DUSP22 (0.77) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL9917038 | 0.82 | DUSP22 (0.77) | MAPTMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108677-A1 | Thioxothiazolidinone Compounds For Use As Pharmaceuticals | KARYON-CTT LTD (FI) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108677-A1 | Thioxothiazolidinone Compounds For Use As Pharmaceuticals | ITGAM, ITGB1, ITGA1 | MAPT 1926/4885MEN1 4099/4885KMT2A 2994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.