Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP22 | Q9NRW4 | 9/20 | 1.00 |
| ▸ | CFTR | P13569 | 5/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.74 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.71 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.71 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12637129 | 0.89 | DUSP22 (0.80) | DUSP22CFTRALDH1A1LMNAPOLB | |
| SCHEMBL24217863 | 0.89 | DUSP22 (1.00) | DUSP22CFTRALDH1A1LMNAPOLB | |
| SCHEMBL10035996 | 0.87 | DUSP22 (0.77) | DUSP22ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL12123516 | 0.87 | DUSP22 (0.77) | DUSP22ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL9917038 | 0.87 | DUSP22 (0.77) | DUSP22ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL24217824 | 0.86 | DUSP22 (1.00) | DUSP22CFTRDUSP3MEN1KMT2A | |
| SCHEMBL1880034 | 0.86 | CFTR (1.00) | DUSP22CFTRMEN1KMT2AMCL1 | |
| SCHEMBL1880031 | 0.86 | CFTR (1.00) | DUSP22CFTRMEN1KMT2AMCL1 | |
| SCHEMBL1880033 | 0.86 | CFTR (1.00) | DUSP22CFTRMEN1KMT2AMCL1 | |
| SCHEMBL6738029 | 0.85 | MAPT (1.00) | DUSP22CFTRALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242993-A1 | METHOD FOR SCREENING MARKERS FOR PREDICTING PROGNOSIS OF RENAL CELL CARCINOMA USING TRANSCRIPTOMIC ANALYSIS | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2023-08-03 | — | — | US | disclosed |
| CN-111434337-B | Use of rhodanine derivatives for the treatment of metabolic disorders | 中国科学院上海营养与健康研究所 | 2023-04-07 | — | — | CN | disclosed |
| US-20040198741-A1 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | WYETH | 2004-10-07 | — | — | US | disclosed |
| US-20030195213-A1 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | BAILEY THOMAS R (US) | 2003-10-16 | — | — | US | disclosed |
| US-20020052396-A1 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | BAILEY THOMAS R (US) | 2002-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195213-A1 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | RXRG, TREH, RARG | DUSP22 4588/4885CFTR 273/4885ALDH1A1 745/4885 |
| US-20020052396-A1 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | RXRG, TREH, RARG | DUSP22 4588/4885CFTR 273/4885ALDH1A1 745/4885 |
| US-20040198741-A1 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | RXRG, TREH, RARG | DUSP22 4588/4885CFTR 273/4885ALDH1A1 745/4885 |
| US-20230242993-A1 | METHOD FOR SCREENING MARKERS FOR PREDICTING PROGNOSIS OF RENAL CELL CARCINOMA USING TRANSCRIPTOMIC ANALYSIS | DUSP15, DUSP22, DUSP2 | DUSP22 2/4885CFTR 4771/4885ALDH1A1 3754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.