Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | POLB | P06746 | 3/20 | 0.78 |
| ▸ | RECQL | P46063 | 3/20 | 0.78 |
| ▸ | NPC1 | O15118 | 3/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.78 |
| ▸ | ALPG | P10696 | 2/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.78 |
| ▸ | HTT | P42858 | 2/20 | 0.78 |
| ▸ | THRB | P10828 | 2/20 | 0.78 |
| ▸ | RAB9A | P51151 | 2/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.78 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.78 |
| ▸ | PKM | P14618 | 1/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.78 |
| ▸ | DUSP22 | Q9NRW4 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6738029 | 0.88 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL12589911 | 0.77 | APP (0.61) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL14213563 | 0.76 | MAPT (0.79) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL13170370 | 0.76 | DUSP22 (0.70) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL14213564 | 0.76 | MAPT (0.78) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL12637129 | 0.75 | DUSP22 (0.80) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL14065931 | 0.75 | MAPT (0.66) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL10491520 | 0.75 | KMT2A (0.76) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL10491519 | 0.75 | KMT2A (0.76) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL11936880 | 0.74 | MEN1 (0.72) | MAPTMEN1KMT2AALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002526-A1 | Phospholipase D inhibitors and uses thereof | CELL THERAPEUTICS, INC. | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002526-A1 | Phospholipase D inhibitors and uses thereof | PLD2, PLD1, PLA2G2D | MAPT 4292/4885MEN1 3009/4885KMT2A 3403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.