Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TRPM5 | Q9NZQ8 | 5/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14066346 | 0.91 | CHRNA7 (0.43) | CHRNA7GAATRPM5TRPA1ALDH1A1 | |
| SCHEMBL263700 | 0.86 | TRPM5 (0.40) | CHRNA7GAATRPM5TRPA1 | |
| SCHEMBL14448261 | 0.78 | CYP1A2 (0.53) | ALDH1A1 | |
| SCHEMBL261140 | 0.77 | POLB (0.63) | — | |
| SCHEMBL263541 | 0.77 | TRPM5 (0.40) | CHRNA7GAATRPM5TRPA1 | |
| SCHEMBL263519 | 0.77 | CHRM5 (0.58) | CHRM5 | |
| SCHEMBL3511383 | 0.77 | POLB (0.63) | — | |
| Hydrochloric Acid SCHEMBL5471928 | 0.77 | CYP1A2 (0.52) | ALDH1A1 | |
| SCHEMBL14066347 | 0.76 | GAA (0.40) | CHRNA7GAAALDH1A1 | |
| SCHEMBL14066345 | 0.76 | HTR3A (0.41) | CHRNA7GAATRPM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429664-B2 | Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof | MEMORY PHARMACEUTICALS CORPORATION (US) | 2008-09-30 | — | — | US | disclosed |