Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5471928 | 0.99 | CYP1A2 (0.52) | CYP1A2RECQLEPHX2MEN1KMT2A | |
| SCHEMBL14448258 | 0.83 | HTR3A (0.58) | EPHX2MEN1KMT2AMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL5467852 | 0.82 | HTR3A (0.57) | EPHX2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL9967270 | 0.81 | RAB9A (0.59) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL1459283 | 0.78 | MEN1 (0.52) | CYP1A2EPHX2MEN1KMT2ALMNA | |
| SCHEMBL14808828 | 0.78 | ALDH1A1 (0.59) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL14066348 | 0.78 | CHRNA7 (0.39) | ALDH1A1 | |
| SCHEMBL3511383 | 0.78 | POLB (0.63) | NPC1RAB9ACYP3A4POLB | |
| SCHEMBL261047 | 0.78 | POLB (0.51) | CYP1A2MEN1KMT2ALMNAMAPT | |
| SCHEMBL261140 | 0.78 | POLB (0.63) | NPC1RAB9ACYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247728-B2 | Bicyclic N-arylamides | BAYER HEALTHCARE AG (DE) | 2007-07-24 | — | — | US | disclosed |
| US-7247728-B2 | Bicyclic N-arylamides | BAYER HEALTHCARE AG (DE) | 2007-07-24 | — | — | US | disclosed |