Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 15/20 | 0.38 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21622308 | 0.86 | DPP8 (0.41) | DPP8DPP9NAMPTTIPARPKDM4E | |
| SCHEMBL9942877 | 0.81 | DPP8 (0.46) | DPP8DPP9NAMPTTIPARPDRD2 | |
| SCHEMBL27916579 | 0.81 | DPP8 (0.40) | DPP8DPP9NAMPTTIPARPKDM4E | |
| SCHEMBL28287616 | 0.81 | DPP8 (0.43) | DPP8DPP9NAMPT | |
| SCHEMBL13102184 | 0.79 | ALDH1A1 (0.45) | DPP8DPP9NAMPTTIPARPLMNA | |
| SCHEMBL30451947 | 0.77 | SIGMAR1 (0.46) | LMNAMAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL3715438 | 0.77 | SIGMAR1 (0.46) | LMNAMAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL2358009 | 0.75 | CARM1 (0.46) | GAA | |
| SCHEMBL26750981 | 0.75 | DPP8 (0.39) | DPP8DPP9NAMPTTIPARPDRD2 | |
| SCHEMBL28566096 | 0.75 | DPP8 (0.42) | DPP8DPP9NAMPTTIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |