Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.54 |
| ▸ | HTR6 | P50406 | 6/20 | 0.50 |
| ▸ | HRH1 | P35367 | 5/20 | 0.50 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 3/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14067790 | 0.90 | HTR6 (0.62) | PTGDR2HTR6HRH1GRIN2B | |
| SCHEMBL14067644 | 0.84 | PTGDR2 (0.56) | AKR1B10AKR1B1PTGDR2HTR6HRH1 | |
| SCHEMBL14067960 | 0.83 | AKR1B10 (0.50) | AKR1B10AKR1B1PTGDR2HTR6HRH1 | |
| SCHEMBL14067961 | 0.82 | AKR1B10 (0.52) | AKR1B10AKR1B1PTGDR2HTR6HRH1 | |
| SCHEMBL14067646 | 0.82 | HTR6 (0.60) | AKR1B10AKR1B1PTGDR2HTR6HRH1 | |
| SCHEMBL14067945 | 0.80 | HTR6 (0.67) | PTGDR2HTR6HRH1PTGDRGRIN2B | |
| SCHEMBL14067789 | 0.79 | TMEM97 (0.45) | AKR1B10AKR1B1PTGDR2HRH1PTGDR | |
| SCHEMBL14067957 | 0.78 | HDAC1 (0.60) | AKR1B10AKR1B1PTGDR2GRIN2BCNR2 | |
| SCHEMBL3724842 | 0.77 | HTR6 (0.62) | HTR6HRH1GRIN2B | |
| SCHEMBL4138331 | 0.77 | HTR6 (0.59) | PTGDR2HTR6HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115098-A2 | SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLES, METHODS FOR THE PRODUCTION AND THE USE THEREOF | ALLA CHEM, LLC (US) | 2008-09-25 | — | — | WO | disclosed |