Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | DDO | Q99489 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745033 | 0.91 | ALDH1A1 (0.61) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL14068682 | 0.88 | HSD17B10 (0.61) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL14068803 | 0.87 | ALDH1A1 (0.68) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL14068800 | 0.86 | KDM4E (0.71) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL14068807 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL14068384 | 0.82 | KDM4E (0.59) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL16491220 | 0.78 | HSD17B10 (0.62) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL4743064 | 0.77 | KDM4E (0.71) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL14068797 | 0.75 | ALDH1A1 (0.74) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL13496402 | 0.75 | KMT2A (0.83) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113006-A1 | METHODS OF USING QUINOLINONE COMPOUNDS IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-18 | — | — | WO | disclosed |