Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | USP2 | O75604 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14068637 | 0.88 | ALDH1A1 (0.58) | HSD17B10KDM4EUSP2ALDH1A1KMT2A | |
| SCHEMBL14068803 | 0.86 | ALDH1A1 (0.68) | HSD17B10KDM4EUSP2ALDH1A1KMT2A | |
| SCHEMBL14068800 | 0.85 | KDM4E (0.71) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL14068807 | 0.84 | ALDH1A1 (0.54) | HSD17B10KDM4EUSP2ALDH1A1KMT2A | |
| SCHEMBL14068384 | 0.81 | KDM4E (0.59) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL4745033 | 0.79 | ALDH1A1 (0.61) | HSD17B10KDM4EUSP2ALDH1A1KMT2A | |
| SCHEMBL4746968 | 0.78 | RXFP1 (0.63) | HSD17B10KDM4EUSP2ALDH1A1KMT2A | |
| SCHEMBL16491220 | 0.77 | HSD17B10 (0.62) | HSD17B10KDM4EUSP2ALDH1A1KMT2A | |
| SCHEMBL4743064 | 0.76 | KDM4E (0.71) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL13496419 | 0.76 | HSD17B10 (0.68) | HSD17B10KDM4EUSP2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113006-A1 | METHODS OF USING QUINOLINONE COMPOUNDS IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-18 | — | — | WO | disclosed |